… Study of the role of TGF-β signaling in high-risk populations, such as the diabetics and the
elderly. Most of our understanding of the role of TGF-β in cardiac remodeling is derived from …

… the current knowledge on the role of TGF-β in infarct healing and cardiac remodeling. …
cardiac remodeling through its direct and potent actions in cardiomyocyte hypertrophy and cardiac …

… of cardiac remodeling. This review briefly summarizes our current knowledge base on cardiac
… remain to be explored to drive the ECM remodeling field forward. Specifically, this review …

… cardiac remodeling … cardiac remodeling, with particular emphasis on those associated with
myocardial infarction. A better understanding of cell signaling involved in cardiac remodeling …

… cardiac disease, and nearly all of them have been shown to impact cardiac signaling pathways
that accelerate cardiac … T-cell (NFAT) signaling pathway has repeatedly been linked to a …

… , 16 , 17 cardiac development, 18 tissue response to injury, 19 and, as will be discussed
in this review, cardiac remodeling and heart failure. Autocrine signaling can contribute to …

… signaling is also activated during cardiac remodeling and heart failure. In this chapter, we will
provide a brief overview of Wnt signaling in … in the development of cardiac hypertrophy, the …

… In summary, the WNT pathway plays a pivotal role in adult cardiac remodeling and may be
suitable for therapeutic interventions. Currently, several molecular and cellular mechanisms …

… Also, neither heart-specific Ctgf deletion nor CTGF overexpression altered cardiac remodeling
and function with aging or after multiple acute stress stimuli. Cardiac fibrosis was also …

Cardiac remodeling involves molecular, cellular, and in-terstitial changes that manifest … 1
Although the term cardiac remodeling was initially coined to describe the prominent changes …