… Cardiac necroptosis signaling is activated in response to pathological stress (eg, MI, I/R, …
that involves the induction of key necroptosis inducers (eg, TNF, FasL, LPS, and TRAIL) and …

… attack and death in the world, is a multifactorial disease caused by the combined impact of
… heart diseases such as valvular heart disease, ischemic heart disease and heart failure [7]. …

… heart disease, accounted for one of every four deaths. As the most common type of heart
disease, coronary heart disease … The possible downstream signaling pathways are discussed in …

… and inflammation in chronic heart failure. Although … signaling, it seems that the inflammatory
response to these stimuli may represent a common final pathogenic pathway in heart failure …

… The aim of this review is to describe the role of tumor necrosis factor-α (TNF-α) in congestive
heart failure (CHF) and the effects of TNF-α blockers in patients with preexisting CHF and …

… pathological processes, including cardiac hypertrophy and heart failure. Emerging data suggest
a link … To show equal loading of protein, β-actin signal from the same blot is included. All …

… Finally, when we investigated the signaling pathway involved in TNFα-induced platelet
O2 - production, a key role played by Arachidonic Acid (AA) metabolism in inducing ROS …

… proinflammatory peptide tumor necrosis factorα (TNF-α) [1]. Direct treatment of cardiomyocytes
with TNF-α causes both … In the heart, both TNF-α and oxidative stress stimulate a variety of …

… TNF in cardiovascular biology and the tumor necrosis factor-alpha synthesis depresses
conpotential role for anti-TNF therapy in heart disease. tractility of isolated rat hearts: evidence …

… tumor necrosis factor α and bacterial lipopolysaccharide (TNFα, LPS) and mitochondrial ETC
dysfunction (ROS signals) … of senescence, aging and diseases of oxidative stress including …