A novel signaling pathway impact analysis
… In the absence of a gold standard, the best alternatives are to: (i) analyze the results of
the pathway analysis method in the light of the existing biological knowledge regarding the …
the pathway analysis method in the light of the existing biological knowledge regarding the …
Ten years of pathway analysis: current approaches and outstanding challenges
… of pathway analysis approaches, our goal here is to group approaches by the type of analysis
… A recent impact factor (IF) analytic approach was proposed to analyze signaling pathways. …
… A recent impact factor (IF) analytic approach was proposed to analyze signaling pathways. …
The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis
JA Papin, BO Palsson - Biophysical journal, 2004 - cell.com
… first such analysis of an actual biological signaling system. Extreme signaling pathway analysis
is a topologically based approach and assumes a balanced use of the signaling network. …
is a topologically based approach and assumes a balanced use of the signaling network. …
Notch signaling in breast cancer: From pathway analysis to therapy
… This review suggests that Notch signaling pathway … signaling pathway regulates the
transcriptional activity of key target genes through crosstalk with several other signaling pathways. …
transcriptional activity of key target genes through crosstalk with several other signaling pathways. …
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Global downstream pathway analysis reveals a dependence of oncogenic NF-E2–related factor 2 mutation on the mTOR growth signaling pathway
… range of biological processes in addition to the antioxidant pathway. … “pathway analysis”
to connect the expression patterns of gene groups with specific phenotypes. This analysis …
to connect the expression patterns of gene groups with specific phenotypes. This analysis …
[HTML][HTML] Pathway analysis of seven common diseases assessed by genome-wide association
A Torkamani, EJ Topol, NJ Schork - Genomics, 2008 - Elsevier
… through Tubby [14], and G-protein GNG2, which modulates Serotonin signaling through …
in our analysis. The serotonin signaling pathway is also implicated in our pathway analysis of …
in our analysis. The serotonin signaling pathway is also implicated in our pathway analysis of …
GAGE: generally applicable gene set enrichment for pathway analysis
… , including the canonical BMP-TGF beta signaling, JAK-STAT signaling, Wnt signaling,
and estrogen signaling pathways–all of which are supported by the experimental literature. …
and estrogen signaling pathways–all of which are supported by the experimental literature. …
Analysis of calcium signaling pathways in plants
O Batistič, J Kudla - Biochimica et Biophysica Acta (BBA)-General Subjects, 2012 - Elsevier
BACKGROUND: Calcium serves as a versatile messenger in many adaptation and developmental
processes in plants. Ca 2+ signals are represented by stimulus-specific spatially and …
processes in plants. Ca 2+ signals are represented by stimulus-specific spatially and …
Pathway analysis of breast cancer genome-wide association study highlights three pathways and one canonical signaling cascade
… trend = 0.0019 for rs12460755) that is absent from the IGF-I signaling pathway. Interestingly,
the fibroblast growth factor signaling pathway was ranked 10th in our study (Table 1; P ES = …
the fibroblast growth factor signaling pathway was ranked 10th in our study (Table 1; P ES = …
Drug cytotoxicity and signaling pathway analysis with three-dimensional tumor spheroids in a microwell-based microfluidic chip for drug screening
Y Chen, D Gao, H Liu, S Lin, Y Jiang - Analytica chimica acta, 2015 - Elsevier
… then lysed on chip followed by signaling transduction pathway analysis. To our knowledge,
… testing and the offline detailed drug signaling pathway analysis combination on one system. …
… testing and the offline detailed drug signaling pathway analysis combination on one system. …