Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

B Kocaadam, N Şanlier - Critical reviews in food science and …, 2017 - Taylor & Francis
… (caspase −8, −3, and −9), tumor suppressor pathway (p53, p21), death receptor pathway (DR4,
DR5), and many cell signal pathways that contain protein kinase pathway (c-Jun N-…

Prospective of curcumin, a pleiotropic signalling molecule from Curcuma longa in the treatment of Glioblastoma

PM Luthra, N Lal - European journal of medicinal chemistry, 2016 - Elsevier
signalling pathways such as PI3K-AKT and RAS oncogenic pathway, p53 tumor suppressor
pathway… Oncogenes, the genes encoding protein components of signaling pathways leading …

Molecular mechanism of curcumin action in signaling pathways: Review of the latest research

P Liczbiński, J Michałowicz… - Phytotherapy …, 2020 - Wiley Online Library
… 1.1 Structure and function of turmeric Turmeric (Curcuma longa L.), is a perennial plant
belonging to the ginger family. Because of its color, it is also called Indian saffron. It grows wild in …

Vasorelaxant effect of curcubisabolanin A isolated from Curcuma longa through the PI3K/Akt/eNOS signaling pathway

JF Chen, F Liu, MM Qiao, HZ Shu, XC Li, C Peng… - Journal of …, 2022 - Elsevier
longa has been reported, we paid more attention to investigate the endothelium-dependent
pathway … applied to further explore the eNOS signaling pathway in the vasorelaxation of …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
… , a component of a spice native to India, was first isolated in 1815 by Vogel and Pelletier
from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical structure of …

Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis

L Camacho-Barquero, I Villegas… - International …, 2007 - Elsevier
Curcumin significantly attenuated the damage and caused … inhibition of p38 MAPK signaling
by curcumin could explain the … JNK signaling pathways in the protective effect of curcumin

[HTML][HTML] Molecular targets for the management of cancer using Curcuma longa Linn. phytoconstituents: A Review

S Sultana, N Munir, Z Mahmood, M Riaz… - Biomedicine & …, 2021 - Elsevier
Curcuma longa and its isolated constituent curcumin are widely evaluated for anticancer
activity. Curcumin … of growth and metastasis by curcumin as signaling pathways. Here C = …

… -type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-κB/MAPK and RIG-1/STAT1/2 signaling pathways

H Ti, Z Mai, Z Wang, W Zhang, M Xiao, Z Yang… - Food & function, 2021 - pubs.rsc.org
… NF-κB/MAPK signaling pathway and compound 4 could significantly … /2 signaling pathways.
Profiles of cytokine mRNAs and proteins suggested that sesquiterpenes from Curcuma longa

Molecular mechanisms of curcumin action: signal transduction

A Shehzad, YS Lee - Biofactors, 2013 - Wiley Online Library
Curcumin is the most active constituent of turmeric and comprises 8% of most turmeric
preparations derived from Curcuma longa. … In summary, multiple apoptotic signaling pathways and …

In silico investigations on curcuminoids from Curcuma longa as positive regulators of the Wnt/β-catenin signaling pathway in wound healing

RAI Reshad, S Alam, HB Raihan, KN Meem… - Egyptian Journal of …, 2021 - Springer
… Wnt/β-catenin signaling pathway plays a significant role in … (curcumin I, curcumin II and
curcumin III) from Curcuma longa to bind and enhance the activity of two intracellular signaling