[HTML][HTML] … protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the …

Z Zhao, J Ning, X Bao, M Shang, J Ma, G Li, D Zhang - Microbiome, 2021 - Springer
… can correct the gut microbiota dysbiosis and ameliorate the rotenone-induced PD mouse
model, in which suppression of the inflammation mediated by the LPS-TLR4 signaling pathway

… insulin signaling pathway and increased glycogen synthase kinase‐3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin

CG Jolivalt, CA Lee, KK Beiswenger… - Journal of …, 2008 - Wiley Online Library
… elements of the insulin signaling pathway and the expression … any effects on the insulin
signaling pathway in the CNS were … insulin signaling pathway in the brain of diabetic mice treated …

In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model

JY Vargas, M Fuenzalida… - Journal of Neuroscience, 2014 - Soc Neuroscience
… Wnt signaling in vivo To study the role of Wnt signaling in the cognitive function of adult
mice, we used WASP-1, a potentiator of Wnt/β-catenin signaling (Beaumont et al., 2007), and …

[HTML][HTML] Signaling pathways from the endoplasmic reticulum and their roles in disease

H Kadowaki, H Nishitoh - Genes, 2013 - mdpi.com
… , diabetes mellitus, cancer, and cardiovascular disease. Thus, ER stress-induced signaling
pathways may serve as potent therapeutic targets of ER stress-related diseases. In this review…

Uric acid demonstrates neuroprotective effect on Parkinson's disease mice through Nrf2-ARE signaling pathway

TT Huang, DL Hao, BN Wu, LL Mao, J Zhang - … and biophysical research …, 2017 - Elsevier
… PD was induced by MPTP intraperitoneally injection for 7 d in male C57BL/6 mice. Mice
were … We showed that uric acid improved behavioral performances and cognition of PD mice, …

[HTML][HTML] TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice

Y Wang, Y Lin, L Wang, H Zhan, X Luo, Y Zeng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… -inflammatory response and its related signaling pathway in the 5xFAD mice model. Finally,
… via the PI3K/AKT/FoxO3a signaling pathway and alleviate cognitive impairment in AD mice. …

[HTML][HTML] Signaling pathway cross talk in Alzheimer's disease

JA Godoy, JA Rios, JM Zolezzi, N Braidy… - … and Signaling, 2014 - Springer
… More recent studies, using small Wnt molecules to activate both canonical and non-canonical
Wnt signaling in vivo, enhances cognition in adult mice and reverses cognitive deficits and …

[HTML][HTML] Notch signaling pathway: architecture, disease, and therapeutics

B Zhou, W Lin, Y Long, Y Yang, H Zhang… - Signal transduction and …, 2022 - nature.com
… NOTCH signaling to illustrate the history, architecture, regulatory mechanisms, contributions
to physiological development, related diseases, … understand the NOTCH signaling pathway. …

Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease

FM Ribeiro, M Paquet, LT Ferreira… - Journal of …, 2010 - Soc Neuroscience
… mGluR5 can activate protective signaling pathways in Hdh Q111/… mice, we tested whether
other signaling pathways activated by mGluRs might be altered in the Hdh Q111/Q111 mice. …

Connecting TNF-α signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by …

R Medeiros, RDS Prediger, GF Passos… - Journal of …, 2007 - Soc Neuroscience
… Intracerebroventricular injection of Aβ 1–40 disrupts learning and memory in mice. The
spatial reference memory version of the Morris water maze test in Swiss mice (n = 9–10 mice per …