… below, all of these Toll genes are candidates to mediate innate immune responses. … Specific
components of microbial cell walls are strong activators of innate immune responses. These …

… new insight into regulation of TLR signaling-triggered innate immune responses. A greater …
signaling may provide new targets for therapeutic intervention for infections and inflammatory …

… We identify the mTOR pathway as a pivotal negative regulator of NF-kB signaling but as a …
of STAT3 signaling in myeloid innate immune cells. Activation of mTOR by inflammatory stimuli …

… receptors on lymphocytes, the innate immune response is mediated primarily by phagocytic
… of signaling pathways ultimately resulting in a proinflammatory innate immune response …

… signaling pathways, every species also exhibits lineage-specific innovations and losses to
their innate immune … deal primarily with the signaling pathways that control innate immunity to …

… signaling pathways play a central role in innate immune Innate immunity is an ancient
biological process that … responses, the role of other signaling events remains poorly understood. …

… Extensive research in the past decade has identified innate immune recognition receptors
and intracellular signaling pathways that culminate in inflammatory responses. Besides its …

… signal recognition of infection and injury. We then describe how the ensuing inflammatory
response is … Finally, we consider inflammatory signaling pathways triggered during allergic or …

… Most importantly, we show that skin commensals are able to amplify the innate immune
response of … act in an additive or synergistic way to amplify immune responses in human skin. …

… that the mammalian innate immune response has ancient … In vertebrates, the innate
immune response not only serves … with the signaling pathways of the insect immune response. …