[HTML][HTML] Signaling pathways and targeted therapy for myocardial infarction

Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
… ; the controller of myocardial fibrosis such as TGF-β/… signaling pathways play an important
role in administering the process of MI, aiming at targeting these aberrant signaling pathways

The role of PI3K/AKT signaling pathway in myocardial ischemia-reperfusion injury

R Deng, J Zhou - International Immunopharmacology, 2023 - Elsevier
signaling pathway after myocardial injury. Interestingly, Notch also activates PI3K/Akt signaling
in the adult myocardium after myocardial injury. … between Notch and Akt signaling [199]. …

Role of the JAK–STAT pathway in myocardial injury

SP Barry, PA Townsend, DS Latchman… - Trends in molecular …, 2007 - cell.com
… The Janus kinase (JAK)–signal transducers and activators of transcription (STAT) pathway
… of the response of the myocardium to various cardiac insults, including myocardial infarction, …

[HTML][HTML] Effects of the TLR4/Myd88/NF-κB signaling pathway on NLRP3 inflammasome in coronary microembolization-induced myocardial injury

Q Su, L Li, Y Sun, H Yang, Z Ye, J Zhao - Cellular Physiology and …, 2018 - karger.com
… the myocardium after CME caused myocardial injury, with involvement of the TLR4/MyD88/NF-κB
signaling pathway… and aggravating myocardial injury. Blocking the TLR4/MyD88/NF-κB …

Dragon's Blood exerts cardio-protection against myocardial injury through PI3K-AKT-mTOR signaling pathway in acute myocardial infarction mice model

C Li, Y Zhang, Q Wang, H Meng, Q Zhang, Y Wu… - Journal of …, 2018 - Elsevier
… effect, Dragon's Blood extract (DBE) was applied on AMI mice model in this study and its
mechanism on inflammation via PI3K-AKT-mTOR signaling pathway was to be validated. …

[HTML][HTML] Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway

J Duan, Y Guan, F Mu, C Guo, E Zhang, Y Yin, G Wei… - Scientific Reports, 2017 - nature.com
… and reduced myocardial apoptosis. We also found that BUT attenuated myocardial injury in
… mice possibly through its anti-oxidant effect via activating AMPK/Akt/GSK-3β/Nrf2 signaling. …

Monomeric CRP aggravates myocardial injury after myocardial infarction by polarizing the macrophage to pro-inflammatory phenotype through JNK signaling pathway

Z Zha, Y Cheng, L Cao, Y Qian, X Liu… - Journal of …, 2021 - Taylor & Francis
… The cardiac function, scar size as well as cardiac fibrosis, infiltration of inflammatory cells,
and the level of proteins in the JNK signaling pathway in infarcted myocardium were assessed. …

Loss of angiotensin-converting enzyme 2 exacerbates myocardial injury via activation of the CTGF-fractalkine signaling pathway

B Song, ZZ Zhang, JC Zhong, XY Yu, GY Oudit… - Circulation …, 2013 - jstage.jst.go.jp
… In mice with cardiac remodeling and injury, MMP-2, MMP-9 and membrane … signaling.However,
the roles of the CTGF-FKN and MMP signaling pathways involved in myocardial injury

[PDF][PDF] LncRNA NEAT1 alleviates sepsis-induced myocardial injury by regulating the TLR2/NF-κB signaling pathway.

SM Wang, GQ Liu, HB Xian, JL Si… - European Review for …, 2019 - europeanreview.org
myocardial injury in mice by inhibiting the TLR2/NF-κB signaling pathway. LncRNA NEAT1
is … to be a potential target for clinical treatment of the sepsis-induced myocardial injury. …

[HTML][HTML] Ginsenoside Rb1 protects against ischemia/reperfusion-induced myocardial injury via energy metabolism regulation mediated by RhoA signaling pathway

YC Cui, CS Pan, L Yan, L Li, BH Hu, X Chang, YY Liu… - Scientific reports, 2017 - nature.com
… In this study, we found that Rb1 significantly inhibited I/R-induced rat myocardial injury, as
… of myocardial morphology and function. In addition, Rb1 administration relieved myocardial