… signaling pathway described in tgf-β signaling pathways … that, although Smad4 is required
for TGF-β-mediated PAI-1 … is more variety in TGF-β signaling pathways than initially supposed. …

… direct interactions among key signaling components. This review does not discuss the cross
talk between TGF-β-activated non-Smad signaling pathways and other signaling pathways. …

… The canonical signaling pathway induced by the TGF-β receptor complex involves the
phosphorylation of Smad proteins which upon activation accumulate in the nucleus and regulate …

… Finally, in the interest of developing future therapies, further studies are warranted to identify
novel points of convergence of TGF-β with other signaling pathways and oncogenic factors …

… For all of the diversity and physiological importance of the responses that this family can elicit,
a disarmingly simple system lies at the core of its signaling pathways in vertebrates, insects…

… Transforming growth factor β (TGF-β) is a central mediator of fibrogenesis. TGF-β is …
discussion of the role of TGF-β-mediated signaling pathways in the pathogenesis of fibrosis. …

… all signal via conserved signaling pathways. The signaling mechanisms of the TGF-β family
… matrix and activation prior to signaling play important roles. At the plasma membrane level, …

… between TGF-β/Smads and other cell signaling pathways will … the non-Smad pathways that
are activated by the TGF-β receptors … These non-Smad pathways include various branches of …

… The identification of the TGFβ cytokine signaling pathway, including … transforming growth
factor β … The signaling pathway that conveys TGFβ inputs from membrane receptors to …

… Transforming growth factor β (TGF-β) and structurally related factors use several intracellular
signaling pathways in addition to Smad signaling … These non-Smad signaling pathways are …