CD95/Fas, non-apoptotic signaling pathways, and kinases

M Le Gallo, A Poissonnier, P Blanco… - Frontiers in …, 2017 - frontiersin.org
… the magnitude of the CD95-mediated non-apoptotic signaling pathways and resistance to …
that the CD95-mediated non-apoptotic signaling pathway counteracts the apoptotic pathway (…

[HTML][HTML] Two CD95 (APO-1/Fas) signaling pathways

C Scaffidi, S Fulda, A Srinivasan, C Friesen, F Li… - The EMBO …, 1998 - embopress.org
… We now have identified two different cell types that use distinct CD95 apoptosis signaling
pathways. Type I cells require activation of caspase-8 at the DISC closely followed by …

Regulation of CD95/Fas signaling at the DISC

IN Lavrik, PH Krammer - Cell Death & Differentiation, 2012 - nature.com
… the apoptotic versus non-apoptotic signaling pathways has non-linear dynamics depending
… of apoptotic versus non-apoptotic signaling pathways in CD95 signaling. The initiation of …

The CD95/CD95L signaling pathway: a role in carcinogenesis

A Fouqué, L Debure, P Legembre - … et Biophysica Acta (BBA)-Reviews on …, 2014 - Elsevier
… the abilities of Fas/CD95, DR4, and DR5 to trigger non-apoptotic signalingsignaling
pathway, but TNFR1 or CD95 stimulation leads to the activation of another cell death signal, …

Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system

M Li-Weber, PH Krammer - Seminars in immunology, 2003 - Elsevier
… Suppression of CD95L expression via cAMP/PKA pathway Reagents that activate the
cAMP signaling pathway have been shown to suppress CD95L expression and CD95-dependent …

The role of CD95 in the regulation of peripheral T‐cell apoptosis

A Krueger, SC Fas, S Baumann… - Immunological …, 2003 - Wiley Online Library
… Nevertheless, this study further substantiates the idea of the CD95 signaling pathway being
an important effector of CD28-mediated costimulation. Taken together, costimulation confers …

Death the Fas way: regulation and pathophysiology of CD95 and its ligand

K Sharma, RX Wang, LY Zhang, DL Yin, XY Luo… - Pharmacology & …, 2000 - Elsevier
… , CD95/APO-1 (Fas) is the best characterized. The specific interaction of Fas with its cognate
ligand, Fassignaling molecules on the cell surface. Recent studies have shown that the …

[HTML][HTML] MAPK/ERK signaling in activated T cells inhibits CD95/Fas‐mediated apoptosis downstream of DISC assembly

TH Holmström, I Schmitz, TS Söderström… - The EMBO …, 2000 - embopress.org
… To narrow down the entry point of the MAPK‐mediated inhibitory signal into the CD95
apoptotic signaling pathway, we tested whether the cleavage of Bid would be affected by MAPK …

Nonapoptotic functions of Fas/CD 95 in the immune response

JP Guégan, P Legembre - The FEBS Journal, 2018 - Wiley Online Library
… affects CD95-mediated signaling through molecular mechanisms that remain to be elucidated.
This review discusses the biological roles of CD95 … and nonapoptotic signaling pathways. …

Fas (CD95)-related apoptosis and rheumatoid arthritis

SL Peng - Rheumatology, 2006 - academic.oup.com
… a current understanding of the Fas (CD95)–Fas ligand (CD178) … by a unique resistance to
Fas-related apoptosis, and agonistic … Impaired Fas signaling pathway is involved in defective T …