Cell signaling pathways related to epithelial mesenchymal transition in cancer metastasis

S Inan, M Hayran - Critical Reviews™ in Oncogenesis, 2019 - dl.begellhouse.com
… cancer cell invasion and metastasis. In cancer progression, similar cell signaling pathways
… to understand the molecular mechanisms of cell signaling pathways related to cancer metas…

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis

JA McCubrey, SL Abrams, TL Fitzgerald… - Advances in biological …, 2015 - Elsevier
… The EGFR/PI3K/PTEN/Akt/mTORC pathway plays prominent roles in malignant … , cancer
initiating cells (CICs) and metastasis. The expression of this pathway is frequently altered in …

The signaling pathways associated with breast cancer bone metastasis

X Song, C Wei, X Li - Frontiers in Oncology, 2022 - frontiersin.org
… bone metastasis. Conclusion: This review focuses on the signaling pathways related to BC
bone metastasis and explores the interactions among these pathways, which will lay a solid …

Notch signaling pathway and cancer metastasis

YY Hu, M Zheng, R Zhang, YM Liang, H Han - Notch Signaling in …, 2012 - Springer
… Recent insights have linked the Notch signaling pathway, a critical pathwaysmetastasis.
This chapter highlights the current evidence for aberration of the Notch signaling in metastasis

Signaling pathways in Ras-mediated tumorigenicity and metastasis

CP Webb, L Van Aelst, MH Wigler… - Proceedings of the …, 1998 - National Acad Sciences
… To test this more directly, we examined the metastatic activities of NIH 3T3 cells transformed
with either the Mos oncogene, a potent activator of MEK (20), or a constitutively activated …

Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways

HH Versteeg, CA Spek, MP Peppelenbosch… - Molecular …, 2004 - Springer
… In this review, we will discuss the links between TF, metastasis, and metastatic behavior of
cells. Understanding the role of the coagulation cascade, and particularly TF, will undoubtedly …

Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy

L Li, P Tang, S Li, X Qin, H Yang, C Wu, Y Liu - Medical oncology, 2017 - Springer
cell fate. In this review, we summarize the roles of Notch signaling pathway in tumor metastasis
… mechanisms and discuss the current treatment strategies targeting Notch signal pathway. …

Cellular signaling pathways implicated in metastasis of colorectal cancer and the associated targeted agents

X Liu, Q Ji, Z Fan, Q Li - Future Oncology, 2015 - Taylor & Francis
… of signaling pathways implicated in CRC metastasis is urgent … cellular signaling pathways
associated with CRC metastasis, … VEGF and JAKs/STAT3 signaling pathways. Targeted agents …

Cell survival and metastasis regulation by Akt signaling in colorectal cancer

E Agarwal, MG Brattain, S Chowdhury - Cellular signalling, 2013 - Elsevier
signaling pathways involved in the process of metastasis will help in effectively targeting
these aggressive cancer cells … the TGFβ/PKA metastatic suppressor pathway that negatively …

Epithelial-to-mesenchymal transition signaling pathways responsible for breast cancer metastasis

B Buyuk, S Jin, K Ye - Cellular and molecular bioengineering, 2022 - Springer
… in these signaling pathways and their regulation in breast cancer metastasis and invasion.
While … controversial, we speculated a convergent signaling network pivotal to elucidating the …