… signaling pathways and driver oncogenes related to thyroid tumorigenesis, focusing on the
MAPK and PI3K pathways, whose relevance as drivers of oncogenesis in the thyroid gland …

… MAPK signaling pathway is physiologically activated by binding of growth factors to receptor
tyrosine kinases (RTKs), such as RET and NTRK, resulting in receptor dimerization and …

… in these signaling pathways and targeted treatments of thyroid cancer were … pathways. In
the present work, the advances in these signaling pathways and targeted treatments of thyroid …

… implicated in thyroid pathology. In this review we focus on the different signaling
pathways involved in TSH-mediated proliferation and their role in thyroid transformation and …

… However, this paper will mainly focus on additional cellular signaling pathways other than
RET responsible of MTC tumorigenesis and progression and potential targeted approaches …

… signaling pathways; microRNA profiles and aberrant methylation have been demonstrated
in more than 70% of DTC. Diagnostic use of these molecular markers may be optimized for …

… carcinomas may … signaling pathways. These distinct genetic alterations constitutively
activate the MAPK, PI3K and β-catenin signaling pathways, which have been implicated in thyroid …

… In this review, we put forth the hypothesis that multiple signaling pathways can ultimately
result in -catenin activation in dedifferentiated thyroid cancer. However, whether these pathways…

… in a broad number of cancers, including thyroid carcinomas. In this review article, the role
of different signaling pathways of PI3K/AKT in thyroid cancers, with the emphasis on the PI3K/…

… Because these signaling proteins function along the same pathway in thyroid cells, this
represents a unique paradigm of human tumorigenesis through mutation of three signaling …