… regulation of the Jun N-terminal kinase (JNK)-signalling pathway can have opposing results
… link the NF-κB pathway to other cell-signalling pathways and asks why integration of NF-κB …

… Therefore, targeted strategies that interfere with NF-κB signalling could offer novel … of
NF-κB in OA pathogenesis and how pharmacological inhibition of the NF-κB signalling pathway …

… of NF-κB activation by increasing the affinity of NF-κB for IκBα. In summary, NF-κB acts at the
crossroads of many signalling pathways… Inappropriate or excessive activation of NF-κB can …

… pathway, which is the predominant NF-κB signalling pathway, … This signal-induced
phosphorylation targets IκB for … the proteasome 7 , thereby releasing NF-κB. The non-canonical …

… Abstract The nuclear factor kappa B (NFκB) signalling pathway regulates the expression
of hundreds of genes that are involved in different cellular processes such as cell proliferation, …

… of extracellular signals (see Pahl, 1999), NF-κB rapidly … for controlling NF-κB activity is the
regulation of the IκB-NF-κB … Almost all signals that lead to activation of NF-κB converge on a …

… talk of cell-signal-transduction pathways play a key … NFκB pathway has been more extensively
studied, it is not to be ignored that the noncanonical pathway (or alternative NFκB pathway…

… The breadth of signals able to activate the NF-κB pathway … of the NF-κB signalling pathway.
The purpose of this review is to catalogue the roles of the different NF-κB primary signalling …

… The signal transduction pathways leading to NF-κB activation are well characterized, and …
implicated in these pathways involve proteins that could constitute targets for NF-κB inhibition. …

… Indeed, some of the key signalling molecules that mediate TLR activation of IRFs were …
NF-κB. Thus, an initial overview of the various TLR signalling pathways that activate NF-κB forms …