过去一年中添加的文章,按日期排序
Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics
3 天前 - … disease pathology between humans and mice. Our result also showed a 175 positive
enrichment for OLIG signature … enrichment for the MG3 signature under all glia conditions, …
enrichment for OLIG signature … enrichment for the MG3 signature under all glia conditions, …
An Enteric Bacterial Infection Triggers Neuroinflammation and Neurobehavioral Impairment in 3xTg-AD Transgenic Mice
3 天前 - … Alzheimer disease (AD)-related neuroinflammatory and neurodegenerative impairment.
However, its causative and mechanistic role in AD pathology … ” signature implicated in …
However, its causative and mechanistic role in AD pathology … ” signature implicated in …
Clinical, neuropathological, and molecular characteristics of rapidly progressive dementia with Lewy bodies: a distinct clinicopathological entity?
GM Bentivenga, S Baiardi, A Mastrangelo… - Alzheimer's Research & …, 2024 - Springer
3 天前 - … a disease duration < 4 years submitted to our prion disease referral centre between
2003 and 2022 who showed Lewy body pathology (… a peculiar clinical signature against the …
2003 and 2022 who showed Lewy body pathology (… a peculiar clinical signature against the …
Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR study
M Daniilidou, J Holleman, G Hagman, I Kåreholt… - Translational …, 2024 - nature.com
4 天前 - … in Alzheimer’s disease (AD). Here, we aimed to identify biomarker signatures
reflecting … and vascular injury were associated with AD pathology, synaptic loss, and worsened …
reflecting … and vascular injury were associated with AD pathology, synaptic loss, and worsened …
Connecting genomic and proteomic signatures of amyloid burden in the brain
6 天前 - … pathology, which may be helpful to understand the underlying biology of the disease.
… publicly accessible through the Alzheimer's Disease Data Initiative (ADDI) community. …
… publicly accessible through the Alzheimer's Disease Data Initiative (ADDI) community. …
Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD
C Colussi, A Bertozzi, L Leone, M Rinaudo… - Stem Cell Research & …, 2024 - Springer
10 天前 - … a pathological signature centered on neurodegeneration/oxidative stress
characterizes the Nup153 protein network in AD-NSCs. However, what makes the Nup153 protein …
characterizes the Nup153 protein network in AD-NSCs. However, what makes the Nup153 protein …
Elucidating the Relationship between Neuroinflammation and Functional Connectivity over the Progression of Alzheimer's Disease
D Chan - 2024 - etda.libraries.psu.edu
17 天前 - … of the hallmarks of Alzheimer’s disease pathology, and that perturbed … signatures
and utilized awake resting state fMRI to study the changes in functional networks over disease …
and utilized awake resting state fMRI to study the changes in functional networks over disease …
Proteomic changes in Alzheimer disease associated with progressive Aβ plaque and tau tangle pathologies
A Pichet Binette, C Gaiteri, M Wennström… - Nature …, 2024 - nature.com
18 天前 - … We unveil protein signatures associated with Aβ and tau … and therapeutics
targeting different disease stages. … pathology compared with those positive for Aβ pathology …
targeting different disease stages. … pathology compared with those positive for Aβ pathology …
CSF proteomic signatures in Alzheimer's disease across amyloid and tau biomarker subgroups
ACMJ Delvenne - 2024 - cris.maastrichtuniversity.nl
18 天前 - … The figure shows neuropathological correlates of pathological suspected non-Alzheimer
disease (AD) pathophysiology (SNAP) and their relationship to AD and non-AD …
disease (AD) pathophysiology (SNAP) and their relationship to AD and non-AD …
Unveiling microglial heterogeneity from single-cell transcriptomics in neurodegenerative diseases
A Palma - bioRxiv, 2024 - biorxiv.org
21 天前 - … and responding to pathological conditions. Their 23 … 31 Moreover, distinct gene
signatures and regulatory … , such as Alzheimer's disease (AD), Parkinson's disease (PD), 46 …
signatures and regulatory … , such as Alzheimer's disease (AD), Parkinson's disease (PD), 46 …