Retinal pathological features and proteome signatures of Alzheimer's disease
… disease progression in the brain remain largely unknown. To better understand the pathological
… , and atrophy correlated with severity of brain Aβ pathology, tauopathy, and atrophy, and …
… , and atrophy correlated with severity of brain Aβ pathology, tauopathy, and atrophy, and …
[HTML][HTML] Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease
… a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD)
pathology … Since late-onset Alzheimer disease (LOAD) participants tend to have age-related …
pathology … Since late-onset Alzheimer disease (LOAD) participants tend to have age-related …
Brain metabolic signatures across the Alzheimer's disease spectrum
A Sala, C Caprioglio, R Santangelo, EG Vanoli… - European journal of …, 2020 - Springer
… We identified hypometabolism signatures for each clinical atypical variant within the AD …
paradigm of neurodegenerative disease, positing that the pathology associated with these …
paradigm of neurodegenerative disease, positing that the pathology associated with these …
A machine learning approach to identify a circulating MicroRNA signature for Alzheimer disease
X Zhao, J Kang, V Svetnik, D Warden… - The journal of …, 2020 - academic.oup.com
… Alzheimer disease (AD) diagnosis. Our results indicate that the serum microRNA signature
… Alzheimer disease (AD) 6 is the most common form of dementia with increasing prevalence …
… Alzheimer disease (AD) 6 is the most common form of dementia with increasing prevalence …
Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults
… consistent with very early AD pathology could be detected in … ) collectively called the cortical
signature of AD based on our … Figure 3 Alzheimer disease (AD)-signature MRI biomarker …
signature of AD based on our … Figure 3 Alzheimer disease (AD)-signature MRI biomarker …
A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets
… signature. In steps 3 and 4, we tested associations between the incipient AD proteomic
signature and both AD pathology … pathology. In step 6b, we validated the incipient AD proteomic …
signature and both AD pathology … pathology. In step 6b, we validated the incipient AD proteomic …
[HTML][HTML] Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?
… We present early evidence for unique pathological signatures of gait in AD and LBD from …
findings provide initial evidence that Alzheimer's disease and Lewy body disease have unique …
findings provide initial evidence that Alzheimer's disease and Lewy body disease have unique …
Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients
F Di Domenico, G Pupo, E Giraldo, MC Badìa… - Free Radical Biology …, 2016 - Elsevier
… Several studies suggest that pathological changes in Alzheimer’s disease (AD) brain begin
around 10–20 years before the onset of cognitive impairment. Biomarkers that can support …
around 10–20 years before the onset of cognitive impairment. Biomarkers that can support …
Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease
… 34,36 to understand the effect of multiple genomic signatures of aging on clinical and pathologic
features of AD, other neurodegenerative diseases, and cerebrovascular disease (CVD). …
features of AD, other neurodegenerative diseases, and cerebrovascular disease (CVD). …
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
… , and also thioflavin-S-negative pathology in corticobasal degeneration and progressive …
of Alzheimer's disease pathology, but was more prominently associated with pathological tau …
of Alzheimer's disease pathology, but was more prominently associated with pathological tau …