… with the onset and pathology of Alzheimer’s disease (AD). … We are able to identify
concordant peripheral signatures … associated with cardiometabolic disease (phosphatidylethanolamine …

… All pathologic substrates were associated with atrophy that involved the inferior and medial
temporal and inferior frontal lobes. Additionally, specific VBM signatures were identified for …

… transcriptional signatures associated with amyloid-beta or pTau pathology in non-disease …
provide both further insights into the different pathology-specific transcriptional responses of …

The joint modeling of genetic data and brain imaging information allows for determining the
pathophysiological pathways of neurodegenerative diseases such as Alzheimer’s disease (…

… To uncover the changes in gene expression in the human brain with an early amyloid
pathology, we performed RNA-seq analysis on the precuneus region derived from brains of …

… characteristic handwriting features associated with this pathology. … signatures collected
from three groups of individuals: DA1 and DA2, with a medical diagnosis of Alzheimer’s disease, …

… These findings suggest that IL-7Rα low aging signature originally found in normal non-AD …
behavior, neuronal senescence, and the pathological phenotypes of Alzheimer's disease [53]. …

Frontiers | Identification of immune microenvironment subtypes and signature genes for
Alzheimer’s disease diagnosis and risk prediction based on explainable machine learning Skip …

… To quantify pathological tau spread to distant brain regions from the injection site, we
compared tau pathology between the ipsilateral and contralateral hippocampus and whole brain. …

… , we created the neuroimaging signatures for each disease by directly comparing the two …
disease-specific signature maps, we obtained individual CTh and FA values for each signature …