… for clinical translation. In this section, we review how the safety of MSNs is influenced by the
intrinsic physicochemical properties of the nanoparticles as … to ensure clinical translation. …

… Based on their performance in clinical trials, silica nanoparticles are emerging as a … However,
key hurdles that remain to be overcome for silica nanoparticles’ clinical translation include …

… Cornell Dots (C-Dots) are hybrid silica nanoparticles that are used for enhancing standard
positron emission tomography (PET)-optical dual-modality imaging, which is an imaging …

… demonstrated the necessary radiochemical stability for clinical applications. The results of …
nanoparticle candidates for in vitro and in vivo biological assessments and product translation…

… clinical translation … silica particles and silica nanoparticles (SNP) with different surface
morphology and modifications. In the middle of 20th century, monodispersed silica nanoparticles …

… herein we provide an overview summarizing the current state-of-the-art and future perspectives
in the design, applications, and clinical translation of ultrasmall and size-optimized silica …

… We describe herein a clinically-translated, integrin-targeting platform for use with both
PET … disease in clinically-relevant larger-animal models can be readily translated into the …

… -triggered cues involves an ultrasmall nanoparticle drug conjugate (NDC) [24], adapted
from a clinically translated sub10 nm fluorescent core-shell silica nanoparticle, C dots [15, 19]. …

… propose three simple criteria to help guide clinical translation of NPs (Table 4). We would
argue that an ideal NP, with a high likelihood of clinical translation, would meet all three criteria…

… are based on consolidated technologies — iron oxide and gold nanoparticles, silica
nanoparticles and liposomes — or molecular complexes resulting from the mixture of relatively …