[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery

Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Silica is “Generally Recognized As Safe” by the United States Food and Drug Administration
(FDA). Recently, silica nanoparticles in the form of Cornell dots (C dots) received FDA …

Organically modified silica nanoparticles: A nonviral vector for in vivo gene delivery and expression in the brain

DJ Bharali, I Klejbor, EK Stachowiak… - Proceedings of the …, 2005 - National Acad Sciences
… organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo
gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-…

Promising gene delivery system based on polyethylenimine-modified silica nanoparticles

M Babaei, H Eshghi, K Abnous, M Rahimizadeh… - Cancer Gene …, 2017 - nature.com
… Surface coating of silica nanoparticles with polycations is an alternative method to … cationic
silica nanoparticles for gene delivery. For example, surface-functionalized silica nanoparticles

A simple plant gene delivery system using mesoporous silica nanoparticles as carriers

FP Chang, LY Kuang, CA Huang, WN Jane… - Journal of Materials …, 2013 - pubs.rsc.org
… utilization of nanoparticles on plant research. Here, we employed functionalized mesoporous
silica nanoparticles (MSNs) to develop a MSN-mediated plant transient gene expression …

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

SB Hartono, NT Phuoc, M Yu, Z Jia… - Journal of Materials …, 2014 - pubs.rsc.org
… In this work, we used PDMAEA covalently attached to the surface of large pore mesoporous
silica nanoparticles (PDMAEA–LPMSNs) to act as a dual delivery system. The surface …

Poly-l-lysine Functionalized Large Pore Cubic Mesostructured Silica Nanoparticles as Biocompatible Carriers for Gene Delivery

SB Hartono, W Gu, F Kleitz, J Liu, L He… - Acs Nano, 2012 - ACS Publications
… We demonstrated in this study that functionalized large pore mesoporous silica
nanoparticles with cubic mesostructure have a true potential for delivery of nucleic acids in high …

Modified silica particles for gene delivery

Z Csőgör, M Nacken, M Sameti, CM Lehr… - Materials Science and …, 2003 - Elsevier
… Inorganic nanoparticles provide new and promising aspects as gene and drug transfer …
Amorphous silica nanoparticles are favoured since SiO 2 is a nontoxic compound present in a lot …

Facile synthesis of monodispersed mesoporous silica nanoparticles with ultralarge pores and their application in gene delivery

MH Kim, HK Na, YK Kim, SR Ryoo, HS Cho, KE Lee… - ACS …, 2011 - ACS Publications
… encapsulation of drugs and genes, large surface area … silica nanoparticles (MMSN)
possessing very large pores (>15 nm) and application of the nanoparticles to plasmid DNA delivery

Silica-based gene delivery systems: From design to therapeutic applications

AM Carvalho, RA Cordeiro, H Faneca - Pharmaceutics, 2020 - mdpi.com
silica nanoparticles in gene delivery systems, either through simple electrostatic interactions
with the surface silanol groups, through covalent silane coupling with trialkoxysilanes, or by …

Capped mesoporous silica nanoparticles as stimuli-responsive controlled release systems for intracellular drug/gene delivery

Y Zhao, JL Vivero-Escoto, II Slowing… - … on drug delivery, 2010 - Taylor & Francis
… in the research of intracellular drug/gene delivery. In particular, numerous surface-functionalized,
end-capped mesoporous silica nanoparticle (MSN) materials have been designed as …