[PDF][PDF] In silico pathway analysis predicts metabolites that are potential antimicrobial targets

M Sarker, S Chopra, K Mortelmans… - J Comput Sci Syst …, 2011 - researchgate.net
pathway analysis to identify bacterial metabolites that fulfill the criteria for drug targets. The
BioCyc interactive metabolic pathway maps and Pathway … , analysis of metabolic pathways, …

[PDF][PDF] In silico analysis of metabolic pathways for identification of putative drug targets for Staphylococcus aureus

VK Morya, V Dewaker, SD Mecarty, R Singh - J Comput Sci Syst Biol, 2010 - academia.edu
… In this study, we have adopted a strategy for comparative metabolic pathway analysis to
find out some potential targets against S. aureus. Only those enzymes which show unique …

METABOLIC PATHWAY ANALYSIS OF S. PNEUMONIAE: AN IN SILICO APPROACH TOWARDS DRUG-DESIGN

S Singh, BK Malik, DK Sharma - Journal of bioinformatics and …, 2007 - World Scientific
… 18 In this study, a strategy of comparative metabolic pathway analysis has been adopted.
The enzymes in the pathways of S. pneumoniae, which do not show similarity to any protein …

[HTML][HTML] A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information

M Alves-Ferreira, ACR Guimarães… - Memorias do Instituto …, 2009 - SciELO Brasil
… Our data from in silico analysis indicate the presence of all the enzymes involved in the
Krebs cycle, corroborating the analyses by KEGG, but also indicated a phosphoenolpyruvate …

In silico Identification of Putative Drug Targets in Pseudomonas aeruginosa Through Metabolic Pathway Analysis

D Perumal, CS Lim, MK Sakharkar - … , PRIB 2007, Singapore, October 1-2 …, 2007 - Springer
… Our in silico approach of comparative metabolic pathway analysis resulted in the identification
of potential drug targets. For the first time, the availability of complete genome sequences …

[HTML][HTML] In silico metabolic pathway analysis identifying target against leishmaniasis–a kinetic modeling approach

N Bora, AN Jha - Frontiers in Genetics, 2020 - frontiersin.org
… This study represents an integration of metabolic pathway and Protein-Protein Interactions
analysis. It consists of incorporating the available experimental data to the theoretical …

[HTML][HTML] Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions

JS Edwards, BO Palsson - BMC bioinformatics, 2000 - Springer
silico analysis to identify seven gene products of central metabolism (glycolysis, pentose
phosphate pathway, … the condition dependent optimal metabolic pathway utilization, and we will …

Essential pathway identification: from in silico analysis to potential antifungal targets in Aspergillus fumigatus

J Thykaer, MR Andersen, SE Baker - Medical mycology, 2009 - Taylor & Francis
… Through a systematic in silico deletion of single metabolic reactions using this model,
several essential metabolic pathways were identified for A. niger. A total of 138 reactions were …

Mycobacterium tuberculosis H37Rv: In Silico Drug Targets Identification by Metabolic Pathways Analysis

A Amir, K Rana, A Arya, N Kapoor… - International journal …, 2014 - Wiley Online Library
… We have performed an in silico comparative analysis of metabolic pathways of the host Homo
… the intracellular metabolism of M. tuberculosis often focus on metabolic pathways that are …

[HTML][HTML] Metabolic pathway analysis for in silico design of efficient autotrophic production of advanced biofuels

P Unrean, KL Tee, TS Wong - Bioresources and Bioprocessing, 2019 - Springer
… Herein, autotrophic metabolism of Cupriavidus necator H16 growing on CO 2 , … metabolic
pathway analysis tools, specifically elementary mode analysis (EMA) and flux balance analysis