Automated benchmarking of peptide-MHC class I binding predictions

T Trolle, IG Metushi, JA Greenbaum, Y Kim… - …, 2015 - academic.oup.com
peptide a rank score for each server and allele. In this case, we assigned the peptide with the
strongest predicted binding a rank score … , for many peptides, all methods make very similar

[HTML][HTML] NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets

M Nielsen, M Andreatta - Genome medicine, 2016 - Springer
… The analysis was done in a similar manner to what we described above, but in addition we
peptides to multiple MHC molecules, we recommend the use of percentile rank scores rather …

[HTML][HTML] Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes

W Zhao, X Sher - PLoS computational biology, 2018 - journals.plos.org
… , on the basis of neighboring MHC bearing the highest sequence similarity. Pan-allele methods
exhibited … The reweighted scores, comprised of MHC protein energy, peptide energy, and …

Peptide length-based prediction of peptideMHC class II binding

ST Chang, D Ghosh, DE Kirschner… - Bioinformatics, 2006 - academic.oup.com
peptideMHC class II binding are typically similar, if not identical, to methods for predicting
peptideMHC … is applied to peptides with multiple registers, the highest score among the …

[HTML][HTML] A community resource benchmarking predictions of peptide binding to MHC-I molecules

B Peters, HH Bui, S Frankild, M Nielsen… - PLoS computational …, 2006 - journals.plos.org
… we will carry out a similar process of exchanging peptides and reagents to ensure consistency
… 3-D structure of the MHC molecules was used to derive scoring matrices. References with …

[HTML][HTML] Enhancing In Silico Protein-Based Vaccine Discovery for Eukaryotic Pathogens Using Predicted Peptide-MHC Binding and Peptide Conservation Scores

SJ Goodswen, PJ Kennedy, JT Ellis - PloS one, 2014 - journals.plos.org
peptide-MHC binding scores could provide contributing evidence to establish a protein’s
potential as a vaccine. Using T-Cell MHC … allele, have similar numbers of binding peptides and …

[HTML][HTML] Peptide binding predictions for HLA DR, DP and DQ molecules

P Wang, J Sidney, Y Kim, A Sette, O Lund, M Nielsen… - BMC …, 2010 - Springer
… with different approaches to removing similar peptides. … experimentally measured, MHC class
II peptide binding affinities … the MHC class II binding affinity datasets, the prediction scores, …

Pan-specific prediction of peptideMHC class I complex stability, a correlate of T cell immunogenicity

M Rasmussen, E Fenoy, M Harndahl… - The Journal of …, 2016 - journals.aai.org
… Evaluating such predictors, we find that the integrative model with similar weight on affinity …
peptide, the predicted stability score, converted half-life in hours, and a percentile rank score. …

The PickPocket method for predicting binding specificities for receptors based on receptor pocket similarities: application to MHC-peptide binding

H Zhang, O Lund, M Nielsen - Bioinformatics, 2009 - academic.oup.com
… a peptide ligand, we use information derived from similar protein … similarity score is 1 for
identical sequences, and can be negative for highly dissimilar sequences. If the similarity score

[HTML][HTML] Prediction of peptides binding to MHC class I and II alleles by temporal motif mining

C Meydan, HH Otu, OU Sezerman - BMC bioinformatics, 2013 - Springer
… Our motif mining method (MHC-PPM) is similar to temporal event mining in time-related …
After scoring every peptide in the training data, any peptide scoring below a predefined …