A review on the methods of peptide-MHC binding prediction

Y Liu, X Ouyang, ZX Xiao, L Zhang… - Current …, 2020 - ingentaconnect.com
… using the similarity scores in the matrix. … peptide-MHC binding affinity to score MHC class
I peptide presentation, thereby improving the performance in natural MHC-binding peptides

Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC alleles

O Schueler-Furman, Y Altuvia, A Sette, H Margalit - Protein Science, 2000 - cambridge.org
peptide can be generated for a given MHC allele, based on experimental binding data of large
ensembles of sequence variants. Peptide candidates can be assigned scores by … a similar

NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction

M Nielsen, O Lund - BMC bioinformatics, 2009 - Springer
… base, SRDS1; sequence similarity reduced UPDS data excluding peptides sharing 9 mer …
The score of a 9 mer peptide was calculated using the conventional feed-forward algorithm. …

In silico quantitative prediction of peptides binding affinity to human MHC molecule: an intuitive quantitative structure–activity relationship approach

F Tian, L Yang, F Lv, Q Yang, P Zhou - Amino Acids, 2009 - Springer
… In this study, physicochemical property scores (DPPS) of amino acids, involving hydrophobicity,
steric properties, electronic properties and hydrogen bond properties, were proposed to …

A structure-based approach for prediction of MHC-binding peptides

Y Altuvia, H Margalit - Methods, 2004 - Elsevier
… to the prediction of MHCpeptide binding was motivated by … of peptideMHC complexes
the peptides adopt a very similarpeptide score is simply the sum of scores over all the peptide’…

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan

M Nielsen, C Lundegaard, T Blicher… - PLoS computational …, 2008 - journals.plos.org
… very similar (ie have binding pockets that are similar to other … the binding core of peptides
bound to MHC class II molecules… nonamer peptides, we assign a normalized binding score, S …

SVRMHC prediction server for MHC-binding peptides

J Wan, W Liu, Q Xu, Y Ren, DR Flower, T Li - BMC bioinformatics, 2006 - Springer
peptide-MHC binding affinities using these models. Benchmarked percentile scores are …
We took an approach similar to the iterative self-consistent (ISC) strategy described earlier […

… peptide libraries and biometric score matrices permit the quantitative analysis of specific and degenerate interactions between clonotypic TCR and MHC peptide …

Y Zhao, B Gran, C Pinilla, S Markovic-Plese… - The Journal of …, 2001 - journals.aai.org
… of TCRs with MHC peptide ligands can be highly flexible, so that many different peptides are
… We call this the Z-index score due to its similarity to statistical Z ratios of means divided by …

POPI: predicting immunogenicity of MHC class I binding peptides by mining informative physicochemical properties

CW Tung, SY Ho - Bioinformatics, 2007 - academic.oup.com
… The immunogenicity class with the highest similarity score was assigned to the test peptide.
If there are multiple peptides with the same score, voting strategy is applied. Otherwise, if two …

Identification of the cognate peptide-MHC target of T cell receptors using molecular modeling and force field scoring

E Lanzarotti, P Marcatili, M Nielsen - Molecular immunology, 2018 - Elsevier
MHC binding peptides. Here, we demonstrate that identification of the cognate target of a TCR
from a set of p:MHC … a similar predicted binding score as the epitope to the corresponding …