… Based on a comparison with the positive control peptide, a binding score was assigned to …
is expected to be similar to the simple scanning for the presence of peptide anchor residues in …

… Algorithms that predict which peptides MHC molecules bind have … different MHC molecules
can be reduced if MHCs with similar … For each allele, the top scoring 1% best binders of one …

… peptide-MHC binding prediction. In this study, we demonstrated that DCNN is able to not only
reliably predict peptide-MHC … 9 physicochemical scores out of 11 physicochemical scores …

… non-mutant peptide, we calculated the similarity score as previously described. Citation73
Briefly, for two peptides a and b the similarity score is calculated as the BLOSUM score for a …

… is based on structural scaffolds of MHC II-peptide complexes and statistical scoring functions
(SSFs). The … II sequence similarity was finally implemented in the methods TEPITOPE [14], …

… peptides to bind these MHC class I molecules. This analysis revealed that despite minimal
sequence similarity in the peptide-… After synthesizing the 9-mer peptides scoring in the upper …

… generating the score matrices. TEPITOPE is the first PSSM method in which the score matrix
… sizes are used to measure the similarity between two peptides. MHC2MIL resorts to multiple …

… , for it to be recognized by the immune system the peptide–MHC complex … a peptide binding
to an MHC may be recognized by a TCR if it binds better with a pIC 50 >6.3 or some similar …

… The binding groove in class II MHC is open at both ends, allowing peptides longer than 9-…
peptides to a MHC class II molecule is difficult because of different lengths of binding peptides …

… generation were used to score peptide alignments by assigning a score to each putative …
population of matrices of high similarity, promoting a linear model of peptide alignment. With the …