Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

L He, AS De Groot, AH Gutierrez, WD Martin, L Moise… - BMC …, 2014 - Springer
peptides that have similarscoring mechanism that accounts for both aspects of immune
recognition, combining the EpiMatrix epitope predictor (to identify peptides that are good MHC

A combined bioinformatic approach oriented to the analysis and design of peptides with high affinity to MHC class I molecules

CA Del Carpio, T Hennig, S Fickel… - Immunology and Cell …, 2002 - Wiley Online Library
… we also seek a matrix or profile similar to M (p,a), but with the fundamental difference that …
the computed interaction scores suggested in the present study, a set of peptides for which the …

NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ

E Karosiene, M Rasmussen, T Blicher, O Lund, S Buus… - Immunogenetics, 2013 - Springer
… recognize peptideMHC complexes on the surface of antigen-presenting cells. Peptides
presented by MHC … The similarity is 1 if the two HLA molecules are predicted to have a perfectly …

Quantitative prediction of MHC-II peptide binding affinity using relevance vector machine

W Zhang, J Liu, Y Niu - Applied Intelligence, 2009 - Springer
… a peptide plays a principle role in peptide and MHC-II binding, and this segment is named
‘binding core’ [2]. Most efforts have been made on how to align the peptidessimilarity scores. …

Predicting peptides that bind to MHC molecules using supervised learning of hidden Markov models

H Mamitsuka - Proteins: Structure, Function, and Bioinformatics, 1998 - Wiley Online Library
… set of data in which each peptide sequence has its own real-valued true score of binding to
… predicted by the HMMs are limited to those having patterns similar to existing patterns having …

Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries

J Sidney, E Assarsson, C Moore, S Ngo, C Pinilla… - Immunome …, 2008 - Springer
… I MHC molecules recognize peptides of 9 to 10 residues in length and carrying residues with
similar … was available for sets of peptides with poorer scores, it was found that peptides with …

A comprehensive assessment and comparison of tools for HLA class I peptide-binding prediction

M Wang, L Kurgan, M Li - Briefings in Bioinformatics, 2023 - academic.oup.com
… , where each peptide has multiple options for MHC restriction)… binding peptides of length
10 shows the similar preference. … 1000 peptides in each tool according to the predicted scores

Structure-based methods for binding mode and binding affinity prediction for peptide-MHC complexes

DA Antunes, JR Abella, D Devaurs… - Current topics in …, 2018 - ingentaconnect.com
Similar to MHC-I … peptide sequence was evaluated using different scoring functions, including
a variety of sequence-based methods and a structure-based scoring function, X-score [142]…

Utility of characteristic QTOF MS/MS fragmentation for MHC class I peptides

H Escobar, E Reyes-Vargas, PE Jensen… - Journal of proteome …, 2011 - ACS Publications
peptide database search algorithms and scoring, not only for MHC peptides but also for other
nontryptic peptide … However, we feel this algorithm (or similar) is important to be aware of …

Improved prediction of MHC II antigen presentation through integration and motif deconvolution of mass spectrometry MHC eluted ligand data

B Reynisson, C Barra, S Kaabinejadian… - Journal of proteome …, 2020 - ACS Publications
… , the MHC II binding cleft is loaded with peptide fragments of … a scoring scheme where the
score of a given peptide was … A similar enrichment has been observed downstream of the …