Simultaneous detection of glutathione and lactate using spectral editing at 3 T

KL Chan, K Snoussi, RAE Edden… - NMR in …, 2017 - Wiley Online Library
… Two spectral editing techniques for the simultaneous detection of glutathione (GSH) and
lactate (Lac) in the human brain at 3 T are described and evaluated. These methods, ‘sMEGA’ (…

Signal enhancement of glutamine and glutathione by single-step spectral editing

L An, MF Araneta, M Victorino, J Shen - Journal of Magnetic Resonance, 2020 - Elsevier
… general and applicable spectral editing approach, in which an always-on editing pulse is
used … perspective, the spectral fitting algorithm used by multi-edit to simultaneously fit the three …

Simultaneous measurement of glutamate, glutamine, GABA, and glutathione by spectral editing without subtraction

L An, MF Araneta, C Johnson… - Magnetic resonance in …, 2018 - Wiley Online Library
… This allows reliable and simultaneous detection of these important markers of glutamatergic
and GABAergic systems and oxidative stress in a single MRS scan from a 2 × 2 × 2 cm 3 …

Simultaneous edited MRS of GABA and glutathione

MG Saleh, G Oeltzschner, KL Chan, NAJ Puts… - Neuroimage, 2016 - Elsevier
… ) compound glutathione (GSH), and single-voxel edited experiments are … We demonstrate
that simultaneous detection of the … showing that simultaneously acquired HERMES spectra are …

Simultaneous editing of GABA and glutathione at 7T using semi‐LASER localization

MG Saleh, M Mikkelsen, G Oeltzschner… - Magnetic resonance …, 2018 - Wiley Online Library
… Because spectral editing is usually applied to lower-concentration compounds, such as
GSH and GABA, relatively long acquisition times are necessary, limiting both the numbers of …

Hadamard editing of glutathione and macromolecule‐suppressed GABA

G Oeltzschner, KL Chan, MG Saleh… - NMR in …, 2018 - Wiley Online Library
… antioxidant glutathione (GSH) are compounds of high importance for the function and
integrity of the human brain. In this study, a method for simultaneous J-difference spectral-edited

A coumarin-based fluorescence sensor for rapid discrimination of cysteine/homocysteine and glutathione under dual excitation wavelengths

J Chao, J Zhao, Y Zhang, F Huo, C Yin - Analyst, 2021 - pubs.rsc.org
detection of the three biothiols; (2) specific identification of one of the three biothiols; (3)
simultaneous … First, we obtained the UV-vis spectra of CB in the DMSO/PBS (v/v, 6/4, pH 7.40) …

Measurement of reduced glutathione (GSH) in human brain using LCModel analysis of difference‐edited spectra

M Terpstra, PG Henry, R Gruetter - Magnetic Resonance in …, 2003 - Wiley Online Library
… While the single shot nature of multiple-quantum editing is advantageous, editing
determination of the frequency and phase in the edited spectra from the simultaneously detected

Simultaneous edited MRS of GABA, glutathione, and ethanol

MG Saleh, M Wang, M Mikkelsen, SCN Hui… - NMR in …, 2020 - Wiley Online Library
Spectral editing reduces signal overlap by selectively targeting … edit EtOH. We perform
simulation, phantom, and in vivo experiments to establish the feasibility of simultaneous detection

1H MRS detection of glycine residue of reduced glutathione in vivo

LG Kaiser, M Marjańska, GB Matson, I Iltis… - Journal of Magnetic …, 2010 - Elsevier
… The second goal is to investigate the possibility of using spectral editing to separate GSH-…
glycine residue and allows for the simultaneous detection of other metabolites, including Glu, …