… reporter expression from DNA-based expression vectors would be slower than that from the
corresponding RNA-based vectors… vector particles. Therefore, the kinetics of reporter protein …

… In this report, we describe a series of defective Sindbis virus helper RNAs which can be
used for packaging Sindbis virus RNA replicons. The defective helper RNAs contain the cis-…

… the Sindbis virus vector … Sindbis virus-derived DNA-based expression vector which can
initiate the replication cascade in transfected mammalian cells to produce high-level expression …

… features of expression vectors based on Sindbis virus, an enveloped plus-stranded RNA
virus (SIN vectors). We will also provide specific examples of the use of SIN vectors for studying …

… viruses as gene expression vectors is their high mutation rates (15). Stability of the CATexpressing …
also infected with Sindbis virus, infectious particles containing the vector RNAs were …

… , SIN and vaccinia virus represent two alternative viral expression systems; if similar …
virus-induced effects on hostcell biology. In addition to the application of dsSIN expression vectors …

… virus expression systems based on the Alphavirus, Sindbis (SIN; Togaviridae). We will describe
the unique biological properties of the mosquito-borne SIN virus … cytoplasmic expression …

… Sindbis viruses and replicons have been useful as vectors for high level foreign gene expression,
but the cytopathic effects of viral … The stability of a long-term expression vector strongly …

… Alphaviruses are RNA enveloped viruses that are proving their value as expression vectors.
… only Sindbis virus and SFV have been considered for other uses. Sindbis virus vectors have …

… of recombinant Sindbis viruses expressing a variety of both viral and … as well as the molecular
mechanisms of viral pathogenesis. … to utilize Sindbis virus as an expression vector under …