Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer

TW Dubensky Jr, DA Driver, JM Polo, BA Belli… - Journal of …, 1996 - Am Soc Microbiol
… to aa 160 of E2 and resulted in a genome length for the Sindbis virus strain used in this
work of 11,700 nt. The viral genomic cDNA was positioned downstream of the bacteriophage …

A neuron-specific gene transfer by a recombinant defective Sindbis virus

BJ Gwag, EY Kim, BR Ryu, SJ Won, HW Ko… - Molecular brain …, 1998 - Elsevier
… In this study, the Sindbis virus-mediated gene transfer was shown to be highly efficient
and selective to neurons compared to glial cells. Cortical neurons infected with rdSind-EGFP …

Alphaviruses: Semliki Forest virus and Sindbis virus vectors for gene transfer into neurons

MU Ehrengruber, S Schlesinger… - Current protocols in …, 2011 - Wiley Online Library
… Alphaviral vectors based on Semliki Forest virus and Sindbis virusvirus and Sindbis virus
exhibit an outstanding preference for neurons rather than glial cells, compared to other viruses

Sindbis virus vector system for functional analysis of apoptosis regulators

JM Hardwick, B Levine - Methods in enzymology, 2000 - Elsevier
… clone of Sindbis virus. The ability of Bcl-2 encoded by the virus to impair Sindbis virus-induced …
Under such conditions, Sindbis virus can be utilized as a gene transfer vector in matured …

[PDF][PDF] Gene transfer: manipulating and monitoring function in cells and tissues

RG Panchal, DA Williams, PD Kitchener… - Clinical and …, 2001 - researchgate.net
… laboratory is using recombinant adeno and Sindbis viruses for gene transfer purposes and
this paper will discuss and review literature related to only these viral gene delivery systems. …

Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein

J Zhang, I Frolov, SJ Russell - … on the science of gene transfer …, 2004 - Wiley Online Library
… Our observations indicate that Sindbis virus provides a promising vector platform for efficient
delivery of a potent cytotoxic transgene coding for a hyperfusogenic gibbon ape leukemia …

A sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo

FW Johanning, RM Conry, AF LoBuglio… - Nucleic acids …, 1995 - academic.oup.com
Gene transfer studies employed synthetic mRNA transcripts … luciferase gene was also cloned
into the sindbis virus vector … followed by sinbis virus non-structural genes required for RNA …

Sindbis virus‐induced silencing of dengue viruses in mosquitoes

ZN Adelman, CD Blair, JO Carlson… - Insect Molecular …, 2001 - Wiley Online Library
… We hypothesize that some mosquito-borne RNA viruses can also be inducers and
targets of gene silencing. We have shown that a double subgenomic Sindbis (dsSIN) virus (Alphavirus…

Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA

I Frolov, E Frolova, S Schlesinger - Journal of virology, 1997 - Am Soc Microbiol
Sindbis virus genomes containing the intact capsid gene of RRV to compare its biological
activity with that of the parental Toto1101 virus and the chimeric virusgene transfer. J. Virol. …

Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures

MU Ehrengruber, K Lundstrom… - Proceedings of the …, 1999 - National Acad Sciences
… We tested the efficacy of SFV- and SIN-mediated gene transfer into organotypic hippocampal
slices from postnatal rats. Slices were cultured on glass coverslips and examined by …