Single-agent versus combination chemotherapy as first-line treatment for patients with advanced non-small cell lung cancer and performance status 2: a literature …

C Mörth, A Valachis - Lung Cancer, 2014 - Elsevier
performance status (PS) 0–1 since it has been shown to be superior to single agent treatment
and marginally superior to non-platinum combinations in terms of overall survival [2], [3]. …

[HTML][HTML] Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: prognostic factors and …

R Lilenbaum, VM Villaflor, C Langer, K O'Byrne… - Journal of Thoracic …, 2009 - Elsevier
… trials were analyzed to evaluate prognostic factors and treatment selection in the first-line
management of advanced non-small cell lung cancer patients with performance status (PS) 2. …

[HTML][HTML] Does very poor performance status systematically preclude single agent anti-PD-1 immunotherapy? A multicenter study of 35 consecutive patients

V Gounant, M Duruisseaux, G Soussi, S Van Hulst… - Cancers, 2021 - mdpi.com
… Anti-PD-1 antibodies prolong survival of performance status (PS) 0–1 advanced non-small-cell
lung cancer (aNSCLC) patients. Their efficacy in PS 3–4 patients is unknown. Conse- …

… pemetrexed versus carboplatin and pemetrexed in patients with advanced non–small-cell lung cancer and Eastern Cooperative Oncology Group performance status …

M Zukin, CH Barrios, J Rodrigues Pereira… - Journal of clinical …, 2013 - ascopubs.org
Purpose To compare single-agent pemetrexed (P) versus the combination of carboplatin and
pemetrexed (CP) in first-line therapy for patients with advanced non–small-cell lung cancer …

[HTML][HTML] First-line single-agent chemotherapy for patients with recurrent or metastatic gastric cancer with poor performance status

JE Hwang, HN Kim, DE Kim… - Experimental and …, 2012 - spandidos-publications.com
… study of recurrent or metastatic gastric cancer patients with poor performance status. In
conclusion, first-line single-agent palliative chemotherapy is tolerated and has a relatively good …

Comparing singleagent with doublet chemotherapy in first‐line treatment of advanced non‐small cell lung cancer with performance status 2: A meta‐analysis

L Luo, Q Hu, J Jiang, X Yang, X Dinglin… - Asia‐Pacific Journal …, 2015 - Wiley Online Library
… The clinical characteristics were matched for performance status, age and tumor stage. All
… plus single agents versus same single agents and two trials compared single agents versus …

Single-Agent Gefitinib in Patients with Untreated Advanced Non–Small-Cell Lung Cancer and Poor Performance Status: A Minnie Pearl Cancer Research Network …

DR Spigel, JD Hainsworth, ER Burkett, HA Burris… - Clinical lung cancer, 2005 - Elsevier
… (NSCLC) and good performance status (PS).Randomized studies have … ) as single-agent
therapy for patients with advanced NSCLC who have progressive disease after platinum agent–…

[HTML][HTML] Phase II trial of single-agent oral vinorelbine in elderly (≥ 70 years) patients with advanced non-small-cell lung cancer and poor performance status

A Camerini, C Valsuani, F Mazzoni, O Siclari… - Annals of …, 2010 - Elsevier
… Elderly patients with advanced non-small-cell lung cancer (NSCLC) with poor performance
status (PS) are a special population requiring particular attention. Single-agent oral …

[HTML][HTML] … phase II trial of single-agent gemcitabine, vinorelbine, or docetaxel in patients with advanced non-small cell lung cancer who have poor performance status …

SS Leong, CK Toh, WT Lim, X Lin, SB Tan… - Journal of Thoracic …, 2007 - Elsevier
… was most marked in patients with performance status 3. … chemotherapy to patients with good
performance status (PS), … benefit in patients treated with single-agent vinorelbine (VIN) over …

Weekly docetaxel as a single agent and in combination with gemcitabine in elderly and poor performance status patients with advanced non-small cell lung cancer

JD Hainsworth, HA Burris III, FA Greco - Seminars in oncology, 2001 - Elsevier
… Group performance status of 0 or I. Actual … with other active single agents. The regimen …
has proven activity when used as a single agent in advanced NSCLC.10-13 It also has shown …