… The present study explores the gene expression changes in immune cells in diabetic kidneys
at a single-cell resolution. The results highlight the alterations in macrophage activation in …

… in the kidney of … cells into different clusters at a proper resolution. Weighted gene co-expression
network analysis was used to identify the key molecules specifically expressed in kidney …

… high level of resolution and depth. Although the application of scRNA-seq in kidney disease
is still in … of kidney cell identities in normal kidneys and cell-specific gene expression during …

… of single cells is not in any way a new concept. Techniques that involve the manipulation of
single cells … of DKD, high resolution microscopy allows the study of individual cells in situ. For …

… with diabetes and is the leading cause of chronic kidney disease worldwide. We used single-
cell … We applied spatially resolved transcriptomic analysis to gain insight into the spatial …

… standard therapy for patients with diabetic kidney disease (DKD). … single-cell RNA sequencing
to profile the kidney cell … of kidney cells with predominant proximal tubular (PT) cells. We …

… single cell level using omics approaches on dissociated tissue, there is little information on
cellular changes in intact kidney … to uncover spatially resolved single cell signatures of DN. …

… 2 diabetes and diabetic kidney disease… single cell resolution transcriptome map of the
kidneys. Then we figured out the communication among the renal and immune cells in the kidneys…

… renal tissue or even in high-resolution compartmentalized … to the disease by using the
single-cell profiles in mixed-cell … diabetic kidney diseases by scRNA-seq of glomerular cells (19). …

… Therefore, it is imperative to carry out a comprehensive analysis of mitochondria
considering heterogeneity among different cell types in kidney of DKD at single-cell resolution. …