… technologies is being witnessed in 2008, with the launch of the first single-molecule DNA
sequencer (… This review discusses several single-molecule sequencing technologies that are …

… by single-molecule fluorescence upon release.16, 17 This Review discusses several
single-molecule DNA sequencing technologies, … Single-molecule DNA sequencing represents an …

… Last, we cover the sequencing of short reads with single-molecule platforms, a suite of … of
sequencing and the amount of information that can be gained from a single sequencing run. …

… , these platforms do not have the sensitivity to detect nucleotides during sequencing of a
single molecule; instead, they rely on clonal amplification to create clusters of molecules [ …

… Recent advances in sequencing technologies exhibit a tendency towards single-molecule
sequencing, which eventually will lead to the commercial implementation of such platforms. …

… since 1971, the interest in sequencing picked up in the late … sequencing technology, known
as Sanger sequencing, after its inventor Frederick Sanger. Continuous DNA sequencing of …

… de novo sequencing throughputs offered by existing capillary methods, unless there are
significant engineering advances or strategies for genome-level single molecule sequencing …

… DNA sequencing technology, where even single DNA molecules can be sequenced, have
inspired dreams of novel technologies for protein sequencing. However, the search for such …

… The genome information has been complemented by a host of ancillary applications making
use of sequencing technologies to shed light on epigenetics, transcription, protein binding, …

… Pacific Biosciences Single Molecule Real-Time (SMRT) sequencing technology has also
been utilized to measure replication fidelity during PCR and has unique advantages for …