Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances

NS Gandhi, RK Tekade, MB Chougule - Journal of Controlled Release, 2014 - Elsevier
therapeutic approach. Recent research focus in the regime … cancer therapy involves the
engagement of targeted delivery of siRNA/miRNA in combinations with other therapeutic agents (…

siRNA-based approaches in cancer therapy

GR Devi - Cancer gene therapy, 2006 - nature.com
… for stabilizing binding conditions, restrictions on permitted target sequences and inefficient
nuclear delivery of oligonucleotides before they can become mainstream for cancer therapy. …

The importance of co‐delivery of nanoparticle‐siRNA and anticancer agents in cancer therapy

N Khelghati… - Chemical Biology & …, 2021 - Wiley Online Library
… Therefore, combination therapy with two or more therapeutic agents is being arisen. One of
… of cancer therapy, we will evaluate combining a variety of anticancer drugs and siRNA with …

Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance

M Creixell, NA Peppas - Nano today, 2012 - Elsevier
… of siRNA, increasing their halflife in blood. ► Treatment using co-delivery systems, rather
than co-treatment, of drugs and siRNA is more effective in overcoming resistance of cancer

Nanoparticle-siRNA: A potential cancer therapy?

SWS Young, M Stenzel, Y Jia-Lin - Critical reviews in oncology/hematology, 2016 - Elsevier
… list of diseases for which siRNA is being tested as a therapeutic agent is extensive. Although
… or utilising single siRNA in conjunction with other therapeutic agents. For example, three …

Efficient nanocarriers of siRNA therapeutics for cancer treatment

MA Subhan, VP Torchilin - Translational Research, 2019 - Elsevier
… small molecule therapeutics simultaneously with siRNA can enhance … siRNA is also a
promising therapeutic agent against a variety of other diseases. siRNA is attractive for therapeutic

Nanocarriers for delivery of siRNA and co-delivery of siRNA and other therapeutic agents

J Zhao, SS Feng - Nanomedicine, 2015 - Taylor & Francis
… Since the outer surface of AuNPs is the only assessable space for loading, the most
straightforward strategy for co-delivery is to load both of the siRNA and the other therapeutic agent

Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy

B Xiao, L Ma, D Merlin - Expert opinion on drug delivery, 2017 - Taylor & Francis
siRNA in the same NP would be much more effective in cancer therapy than application of
chemical agent or siRNA … -deliver therapeutic agents and siRNAs for cancer therapy and have …

Inhalable siRNA: potential as a therapeutic agent in the lungs

N Durcan, C Murphy, SA Cryan - Molecular pharmaceutics, 2008 - ACS Publications
… of targeted delivery of small interfering RNA (siRNA) to the lungs must be developed. … in
siRNA delivery to airway cells in vitro and the work to date on in vivo delivery of siRNA to the …

Progress in natural compounds/siRNA co-delivery employing nanovehicles for cancer therapy

M Ashrafizadeh, A Zarrabi, K Hushmandi… - ACS combinatorial …, 2020 - ACS Publications
therapeutic agents/small interfering RNA (siRNA) as a potent gene-editing tool in cancer
therapy … In the present review, co-delivery of natural compounds/siRNA using nanovehicles are …