Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC‐1α mediated attenuation of mitochondrial oxidative stress
T Zhang, Y Chi, Y Kang, H Lu, H Niu… - Journal of cellular …, 2019 - Wiley Online Library
… on SIRT1/PGC-1α mediated mitochondrial function has not been reported. It has been suggested
that SIRT1 can increase the expression of PGC-… that the expression of SIRT1, PGC-1α, …
that SIRT1 can increase the expression of PGC-… that the expression of SIRT1, PGC-1α, …
Placental mesenchymal stem cells alleviate podocyte injury in diabetic kidney disease by modulating mitophagy via the SIRT1-PGC-1alpha-TFAM pathway
X Han, J Wang, R Li, M Huang, G Yue, L Guan… - International Journal of …, 2023 - mdpi.com
… and mitophagy and significantly increased the expression of SIRT1, PGC-1α, and … podocyte
injury and PINK1/Parkin-mediated mitophagy inhibition in DKD by activating the SIRT1-PGC-…
injury and PINK1/Parkin-mediated mitophagy inhibition in DKD by activating the SIRT1-PGC-…
[HTML][HTML] The mitochondrial SIRT1–PGC-1α axis in podocyte injury
S Tsuruoka, A Hiwatashi, J Usui, K Yamagata - Kidney international, 2012 - Elsevier
… They further showed that overexpression of SIRT1 or PGC-1α inhibited the … and podocyte
injury. Resveratrol, an activator of SIRT1, protected mitochondrial function against podocyte …
injury. Resveratrol, an activator of SIRT1, protected mitochondrial function against podocyte …
Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia–reperfusion injury
JA Funk, RG Schnellmann - Toxicology and applied pharmacology, 2013 - Elsevier
… PGC-1α expression and induced mitochondrial and podocyte injury, and that this could be
reversed with SIRT1 … Additionally, Tran et al., provided evidence that PGC-1α expression was …
reversed with SIRT1 … Additionally, Tran et al., provided evidence that PGC-1α expression was …
[HTML][HTML] Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury
… SIRT1 activity by BF175 induces deacetylation of PGC-1α … SIRT1 expression in podocytes
or the activation of SIRT1 by a new agonist BF175 attenuates albuminuria and podocyte injury …
or the activation of SIRT1 by a new agonist BF175 attenuates albuminuria and podocyte injury …
Reduction in podocyte SIRT1 accelerates kidney injury in aging mice
PY Chuang, W Cai, X Li, L Fang, J Xu… - American Journal …, 2017 - journals.physiology.org
… of podocyte-specific reduction of Sirt1 in age-induced kidney injury. We employed the inducible
… In this study, we used an inducible podocyte-specific knockdown mouse model of Sirt1 to …
… In this study, we used an inducible podocyte-specific knockdown mouse model of Sirt1 to …
Epigenetic regulation through SIRT1 in podocytes
Y Nakatani, R Inagi - Current hypertension reviews, 2016 - ingentaconnect.com
… Here, we confirmed that SIRT1 protects podocytes by maintaining PGC-1α via its deacetylase-…
dysfunction and podocyte injury via the effect of resveratrol treatment as a SIRT1 activator. …
dysfunction and podocyte injury via the effect of resveratrol treatment as a SIRT1 activator. …
Formononetin attenuates renal tubular injury and mitochondrial damage in diabetic nephropathy partly via regulating sirt1/PGC-1α pathway
Q Huang, H Chen, K Yin, Y Shen, K Lin… - Frontiers in …, 2022 - frontiersin.org
… cell injury and mitochondrial dysfunction in DN animals and the protective effects of FMN on
podocyte injury … injury and mitochondrial damage in diabetic rats partly through regulating …
podocyte injury … injury and mitochondrial damage in diabetic rats partly through regulating …
[HTML][HTML] SIRT1 alleviates aldosterone-induced podocyte injury by suppressing mitochondrial dysfunction and NLRP3 inflammasome activation
M Jiang, M Zhao, M Bai, J Lei, Y Yuan, S Huang… - Kidney …, 2021 - karger.com
… of Sirt1 aggravated aldosterone-induced podocyte injury … )-18, and caspase-1 expression
after Sirt1 knockout. We observed that … revealed that SIRT1 protects against podocyte injury via …
after Sirt1 knockout. We observed that … revealed that SIRT1 protects against podocyte injury via …
[HTML][HTML] Sirtuins as novel pharmacological targets in podocyte injury and related glomerular diseases
T Liu, L Yang, H Mao, F Ma, Y Wang, S Li, P Li… - Biomedicine & …, 2022 - Elsevier
… SIRT1 was found to maintain the stabilization of podocyte actin cytoskeleton by … RSV can
restore the expression of SIRT1 and PGC-1α and inhibit excessive ROS production, thereby …
restore the expression of SIRT1 and PGC-1α and inhibit excessive ROS production, thereby …
相关搜索
- podocyte injury mitochondrial dysfunction
- podocyte injury in diabetic kidney disease
- podocyte injury pgc 1α axis
- sirt1 pgc 1α pathway mitochondrial damage
- podocyte injury and proteinuria
- mediated attenuation podocyte damage
- injured podocytes actin cytoskeleton by deacetylation
- podocyte depletion pgc 1α overexpression
- podocyte injury wnt1 β catenin pathway
- podocyte injury pgc 1alpha
- sirt1 pgc grape seed procyanidin
- sirt1 pgc placental mesenchymal stem cells
- mitochondrial oxidative stress podocyte damage
- podocyte injury sirt6 deficiency
- diabetic mice podocyte damage
- podocyte injury nlrp3 inflammasome activation