Skeletal muscle mitochondrial dysfunction & diabetes

R Sreekumar, KS Nair - Indian Journal of Medical Research, 2007 - journals.lww.com
… causes muscle mitochondrial dysfunction. The basis of the above hypothesis is that insulin …
muscle mitochondrial biogenesis23. It has been observed that the activity of the mitochondrial

Decline in skeletal muscle mitochondrial function with aging in humans

KR Short, ML Bigelow, J Kahl… - Proceedings of the …, 2005 - National Acad Sciences
… These results demonstrate that age-related muscle mitochondrial dysfunction is related
to reduced mtDNA and muscle functional changes that are common in the elderly. …

Skeletal muscle mitochondrial dysfunction during chronic obstructive pulmonary disease: central actor and therapeutic target

A Meyer, J Zoll, AL Charles, A Charloux… - Experimental …, 2013 - Wiley Online Library
… This review focuses on mitochondrial involvement in limb skeletal muscle alterations (…
on mitochondrial dysfunction in limb skeletal muscles and examines whether this dysfunction

Hyperammonaemia‐induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress

G Davuluri, A Allawy, S Thapaliya… - The Journal of …, 2016 - Wiley Online Library
… Increased skeletal muscle ammonia uptake and … mitochondria via glutamate synthesis from
α-ketoglutarate resulting in cataplerosis. We show skeletal muscle mitochondrial dysfunction

Is skeletal muscle mitochondrial dysfunction a cause or an indirect consequence of insulin resistance in humans?

JF Dumas, G Simard, M Flamment, PH Ducluzeau… - Diabetes & …, 2009 - Elsevier
… the link between skeletal muscle mitochondrial dysfunction and … , mitochondria are functionally
impaired (dysfunction in the … of mitochondria or to a combination of this and mitochondrial

Mitochondrial dysfunction in skeletal muscle pathologies

J Abrigo, F Simon, D Cabrera, C Vilos… - Current Protein and …, 2019 - ingentaconnect.com
… in the muscle is that this tissue has a high mitochondrial content … the muscle during pathologies
that produce skeletal muscle atrophy … of mitochondrial dysfunction during muscle wasting. …

Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance

J Hoeks, NA van Herpen, M Mensink… - Diabetes, 2010 - Am Diabetes Assoc
skeletal muscle mitochondrial functional capacity in humans to examine whether the
mitochondrial dysfunction … a direct available energy source for the muscles and is paralleled by an …

Skeletal muscle mitochondrial dysfunction is present in patients with CKD before initiation of maintenance hemodialysis

JL Gamboa, B Roshanravan, T Towse… - Clinical Journal of the …, 2020 - journals.lww.com
Skeletal muscle mitochondria are important for physical … that mitochondrial dysfunction is
associated with the severity of CKD. We also evaluated the interaction between mitochondrial

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction

HM De Feyter, NMA Van den Broek… - European journal of …, 2008 - academic.oup.com
… We examined in vivo skeletal muscle mitochondrial function … the proposed role of mitochondrial
dysfunction in the aetiology … suggest that skeletal muscle mitochondrial dysfunction does …

Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy

A Kumar, G Davuluri, N Welch, A Kim… - Free Radical Biology …, 2019 - Elsevier
… causes skeletal muscle mitochondrial dysfunction, decreased protein synthesis, and
increased autophagy, and that these perturbations are reversed by targeting mitochondrial ROS. …