… -melanoma skin cancers. … skin dysfunction in patients with skin cancers has provided a
strong basis for the development of novel therapeutic strategies for these obdurate groups of skin …

… and MMP25 by RANKL stimulation, TAMs in skin cancer of apocrine origin produce MMP1
and … of these skin cancers, and might be targets for molecular-targeted therapy in the future. …

… of COX-2 in mouse and human skin contributes to the development of skin cancer. … and
number of UVBinduced mouse skin cancers and decreases COX-2 activity in skin tumours.…

… genes in these cancers provide new potential therapeutic targets. These alterations … target
these specific proteins may represent promising approaches to therapy of human skin cancers…

… Therefore, programmed cell death protein 1 (PD-1) receptor has been elected a therapeutic
target, and antibodies against PD-1 such as PDR001 are being tested in melanoma clinical …

… There is hope that pro‐apoptotic strategies will lead to pronounced therapeutic success
against skin cancer. Importantly, the involvement of the different pro‐apoptotic pathways in …

… In this paper we will review new therapeutic pharmacological approaches for nonmelanoma
skin cancer (NMSC) that are based on molecular evidences accumulated in the past years (…

… skin cancer, starting from the signaling pathways involved, newer developed drugs with their
targets … a significant role in the management and treatment of different types of skin cancer. …

… skin cancer statistics. Current treatment modalities such as surgery, radiotherapy, conventional
chemotherapy, targeted therapy… to declined anti-skin cancer therapeutic efficacy and poor …

… be highly expressed in several skin cancers, including malignant melanoma, … targeted
therapies and ADCs against Nectin-4 could therefore be novel therapeutic options for skin cancers…