… responsive leading to autoantibody production, various T cells also play different roles in …
different T cells subsets contribute to systemic lupus erythematosus pathogenesis and how …

… cells and their signature cytokine IL-17, contribute to the pathogenesis of SLE and especially
lupus … -17-producing T cells in kidneys of lupus prone mice and patients with lupus nephritis …

… in SLE. Further studies on the roles of these distinct cell death pathways will deepen our
comprehension of SLE pathogenesis and promote the development of therapeutic strategies for …

… With the discovery of new innate immune cells and … immune cells and molecules in promoting
and potentiating SLE. … innate immune cells and pathways in the pathogenesis of SLE. We …

… systemic lupus erythematosus. In order to therapeutically target B … pathogenic role played
by B cells in lupus, including a discussion of the importance of different B cell subsets in lupus …

… However, B cells can contribute to SLE pathogenesis through additional pathways. For
example, lupus-prone MRL/lpr mice that are made B cell-deficient exhibit a markedly attenuated …

… BCR signaling in SLE B cells and IL-6 down-… cells in SLE patients [17]. Apart from its systemic
effects, IL-6 was shown to have a particularly close link with the renal manifestation of SLE. …

… Multiple SLE-associated autoreactive antibodies, which are found in both SLE patients and
lupus … It has been demonstrated that the pathogenic autoantibodies result from CD4 + T cell-…

… in the understanding of SLE pathogenesis placed the innate … in understanding the SLE
immune-pathogenesis with a … and T cell involvement in the SLE pathogenesis mechanisms …

… IL-17 in other cell types may contribute to SLE pathogenesis. … blood mononuclear cells of
patients with lupus nephritis was … participate in the activation of B cells in patients with SLE. …