… SLE PBMCs and lupus patients-derived cell lines (37). Type I IFN is recognised as the central
player in SLE pathogenesis … and SLE disease activity, also known as the "IFN signature" of …

… concanamycin A inhibits the killing of autologous monocytes by lupus CD4+ T cells,
which suggests a potential pathogenic role for perforin demethylation and overexpression in …

… The pathogenesis of SLE is attributed to dysfunction of T cells, B … of T cells from patients
with SLE (n = 33) and from lupus-prone mice, the latter effect is caused by T-cell depletion of …

… B cell subset was named as age-associated B cells (ABCs) and found to be expanded during
SLE pathogenesis in … pathogenic role of ABCs in lupus mice and SLE patients (Figure 1). …

… cell type abnormalities are involved in the pathogenesis of … of autoreactive B cells,
abnormalities in numerous T-cell subsets … of CD8 + T cells in SLE pathogenesis and review how …

… pathogenesis, as these cells are few in … lupus erythematosus. This review focuses on
research that could help define the role of natural killer cells in systemic lupus erythematosus and …

… debris is removed immediately in a healthy homeostatic state, the excessive upregulation
of apoptosis caused by elevated ROS in SLE exposes cell debris to antigen-presenting cells …

… in lupus erythematosus. In this review, we discuss recent literature investigating pathogenetic
mechanisms of lupus … into pathogenic potential of autoreactive T cells in lupus nephritis. …

… cells undergo apoptosis. This observation suggests that apoptotic cells are an important source
of antigenic material in SLE… that immunization of mice with apoptotic cells can lead to the …

… The key cytokine that is involved in SLE pathogenesis is interferon alpha. Interferon …
Dysregulated cytokine expression by T cells contributes to pathogenesis of SLE. SLE T cells secrete …