[HTML][HTML] Peptidergic signaling from clock neurons regulates reproductive dormancy in Drosophila melanogaster

D Nagy, P Cusumano, G Andreatta, AM Anduaga… - PLoS …, 2019 - journals.plos.org
… Since sNPF is widely present in the nervous system [53,55], we started by overexpressing
this neuropeptide with a pan-neuronal driver. This manipulation (elav>2xsNPF) produced a …

[HTML][HTML] Coupling neuropeptide levels to structural plasticity in Drosophila clock neurons

A Herrero, T Yoshii, JI Ispizua, C Colque, JA Veenstra… - Current Biology, 2020 - cell.com
… The small LNvs (sLNvs) together with the large LNvs (lLNvs) are the only circadian neurons
in the Drosophila brain that express the neuropeptide pigment dispersing factor. Pigment …

[HTML][HTML] Neuropeptide F inhibits dopamine neuron interference of long-term memory consolidation in Drosophila

KL Feng, JY Weng, CC Chen, MB Abubaker, HW Lin… - IScience, 2021 - cell.com
… Olfactory memory in Drosophila involves convergent projection neuron (PN; odor) and …
interferes with aversive LTM formation; (2) neuropeptide F (NPF) signaling blocks this interference …

[HTML][HTML] Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive

Y Ki, C Lim - Elife, 2019 - elifesciences.org
… of wake, particularly in a subset of clock neurons that express the circadian neuropeptide
PIGMENT-DISPERSING FACTOR (PDF) (Liu et al., 2014a). Subsequently, WAKE acts as a …

[HTML][HTML] The GABAA receptor RDL acts in peptidergic PDF neurons to promote sleep in Drosophila

BY Chung, VL Kilman, JR Keath, JL Pitman, R Allada - Current Biology, 2009 - cell.com
… We assessed sleep-wake modulation by a core set of circadian pacemaker neurons that
express the neuropeptide PDF. We find that disruption of PDF function increases …

[HTML][HTML] Postprandial sleep mechanics in Drosophila

KR Murphy, SA Deshpande, ME Yurgel, JP Quinn… - Elife, 2016 - elifesciences.org
… stems from an alternative neuropeptide or neurotransmitter. By … a waking response. This
suggests that ingested protein promotes both sleep and wakefulness, and that the wakefulness

[HTML][HTML] Dynamic neuronal instability generates synaptic plasticity and behavior: Insights from Drosophila sleep

M Tabuchi - Neuroscience research, 2024 - Elsevier
… of the neurophysiological patterns of specific sleep/wake circuits in Drosophila, which is …
that mediate homeostatic and circadian regulation of sleep in Drosophila. Based on work in the …

[HTML][HTML] The neuropeptide galanin is required for homeostatic rebound sleep following increased neuronal activity

S Reichert, OP Arocas, J Rihel - Neuron, 2019 - cell.com
… For example, in Drosophila, two sleep regulatory neuron classes alter electrophysiological
… Here, we develop a pharmacological assay to decouple sleep pressure from prior waking

Disrupting flight increases sleep and identifies a novel sleep-promoting pathway in Drosophila

K Melnattur, B Zhang, PJ Shaw - Science advances, 2020 - science.org
… In addition, we identified a critical neuropeptide (burs) … sleep, Drosophila is a relatively
recent entrant to sleep research (9). However, as with the mammalian system, fly sleep and wake

[HTML][HTML] Neurexin regulates nighttime sleep by modulating synaptic transmission

H Tong, Q Li, ZC Zhang, Y Li, J Han - Scientific reports, 2016 - nature.com
… Here, we show that lack of the Drosophila α-neurexin … use neuropeptides to maintain
sleep by investigating the sleep-… by the interaction between sleep-promoting and wake-promoting …