Safety aspects of treatment with lacidipine—a slow-onset, long-acting calcium antagonist

LH Lindholm, P Tcherdakoff, A Zanchetti - Blood pressure, 1996 - Taylor & Francis
… molecule with a gradual onset of activity, protracted duration of … The aim of the present paper
was to review the clinical safety … (EU) guidelines on drug safety stress that it is important to …

Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability

A Schulze-Bonhage, M Hintz - Patient preference and adherence, 2015 - Taylor & Francis
… or older with partial-onset seizures with or without secondary … , anxiety, and aggression,
slow titration and close monitoring … Preclinical aspects of human PER exposure are included in …

Late-onset MS: disease course and safety-efficacy of DMTS

MC Buscarinu, R Reniè, E Morena, C Romano… - Frontiers in …, 2022 - frontiersin.org
… The advanced age exerts a great impact in the main aspects … aging process influences the
onset and the clinical course of … not statistically related with a slowing of disability progression (…

Safety and efficacy of intravenously administered tedisamil for rapid conversion of recent-onset atrial fibrillation or atrial flutter

SH Hohnloser, P Dorian, M Straub, K Beckmann… - Journal of the American …, 2004 - jacc.org
… Its efficacy and safety for conversion of recent onset AF or … good clinical efficacy but also with
a favorable safety profile. … and safety of tedisamil for rapid conversion of recent-onset AF or …

Slow Onset Disasters

G Salvalai, E Quagliarini, JDB Cadena, G Bernardini - Springer
This book collects the results obtained during three years of activity by a research team from
Politecnico di Milano led by Professor Graziano Salvalai and the team coordinated by Prof. …

An update on the management of young-onset Parkinson's disease

N Klepac, M Habek, I Adamec, AK Barušić… - Degenerative …, 2013 - Taylor & Francis
… handicap, as well as individual aspects of comorbidity and age. … pallidotomy is a completely
safe procedure. Citation101 … with younger age at onset have slower disease progression, an …

Resilient and User-Centered Solutions for a Safer Built Environment Against Sudden and Slow Onset Disasters: The BE S2ECURe Project

E Quagliarini, E Currà, F Fatiguso, G Mochi… - Sustainability in Energy …, 2020 - Springer
… BE features which can mainly affect its safety (and those of its … to correlate SUODs to SLODs
aspects in such BETs. Strategy … be devoted to understand human safety level and strategies …

Risky business: Covering slowonset hazards as rapidly developing news

L Wilkins, P Patterson - Political Communication, 1990 - Taylor & Francis
… It appears that typical media coverage patterns of both slow- and quick-onset hazards,
and their resulting risks, play into this precise cognitive pattern. The media signal- …

A comprehensive review of rapid-onset opioids for breakthrough pain

H Smith - CNS drugs, 2012 - Springer
… for the approved rapid-onset opioids, which comprise different … safety of the approved
rapid-onset opioids are comparable. … unacceptable for BTP gave “slow onset of analgesia” as their …

Management of recent-onset sustained atrial fibrillation: pharmacologic and nonpharmacologic strategies

DH Lau, J Kalman, P Sanders - Clinical Therapeutics, 2014 - Elsevier
… -line agent because of lower efficacy with slower onset of action and poor heart rate control
… recent-onset sustained AF. In addition to the rate and rhythm control aspects of management, …