Twenty years of phase III trials for patients with extensive-stage small-cell lung cancer: perceptible progress

JP Chute, T Chen, E Feigal, R Simon… - Journal of clinical …, 1999 - ascopubs.org
III trials were identified based on the statement of the authors in the published reports and
were verified by contacting the group chair. A small minority of the phase III trials … phase III trials

Twenty-two years of phase III trials for patients with advanced non–small-cell lung cancer: Sobering results

OS Breathnach, B Freidlin, B Conley… - Journal of Clinical …, 2001 - ascopubs.org
… Forty-three randomized, controlled phase III trials initiated between 1973 and 1994 in North
… with advanced non–small-cell lung cancer were identified. Ten trials were found to be …

[HTML][HTML] Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results

I Oze, K Hotta, K Kiura, N Ochi, N Takigawa… - PloS one, 2009 - journals.plos.org
… chemo-naïve patients with advanced non-small cell lung cancer (NSCLC) enrolled in phase
III trials. The analysis similarly revealed a very small increase in patient survival (3.61 days …

Sequential vs concurrent chemoradiation for stage III non–small cell lung cancer: randomized phase III trial RTOG 9410

WJ Curran Jr, R Paulus, CJ Langer… - … the National Cancer …, 2011 - academic.oup.com
… status patients with stage III non–small cell lung cancer. However, it is not known whether
sequential or concurrent delivery of these therapies is the optimal combination strategy. …

Immunotherapeutic approaches for small-cell lung cancer

WT Iams, J Porter, L Horn - Nature Reviews Clinical Oncology, 2020 - nature.com
… Results from three phase III trials exploring the efficacy of this … 1 Outcomes of immunotherapy
trials in small-cell lung cancer … In this open-label, randomized, phase III trial, 268 patients …

[HTML][HTML] Small cell lung cancer

G Rosti, G Bevilacqua, P Bidoli, L Portalone, A Santo… - Annals of …, 2006 - Elsevier
… Phase II trial of biweekly irinotecan plus gemcitabine … II study of imatinib in patients with
small cell lung cancer Clin … II study of imatinib in patients with small cell lung cancer. Clin …

[HTML][HTML] … cisplatin and etoposide in patients with completely resected stage I-IIIa small cell lung cancer: the Japan Clinical Oncology Lung Cancer Study Group Trial  …

R Tsuchiya, K Suzuki, Y Ichinose, Y Watanabe… - The Journal of thoracic …, 2005 - Elsevier
… From September 1991 through December 1996, 62 patients with completely resected small
cell lung cancer who were less than 76 years of age from 17 centers were entered in the trial

Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial

ES Kim, V Hirsh, T Mok, MA Socinski, R Gervais, YL Wu… - The Lancet, 2008 - thelancet.com
… Docetaxel (75 mg/m 2 ) was approved for second-line treatment of advanced non-small-cell
lung cancer after findings from two phase III trials TAX 317 and TAX 320 showed improved …

… phase III trial of vinorelbine plus cisplatin compared with observation in completely resected stage IB and II non–small-cell lung cancer: updated survival analysis of …

CA Butts, K Ding, L Seymour… - Journal of clinical …, 2010 - ascopubs.org
… Adjuvant cisplatin-based chemotherapy (ACT) is now an accepted standard for completely
resected stage II and III A non–small-cell lung cancer (NSCLC). Long-term follow-up is …

Small cell lung cancer

GP Kalemkerian, W Akerley, P Bogner… - … Comprehensive Cancer …, 2013 - jnccn.org
… Initially, a small phase III trial performed in Japan reported … However, 2 subsequent large
phase III trials performed in the … A randomized phase II trial (n=70) comparing carboplatin and …