… II study of gemcitabine plus cisplatin or carboplatin, with or without cetuximab, as first-line therapy for patients with advanced or metastatic non–small-cell lung cancer

CA Butts, D Bodkin, EL Middleman… - Journal of Clinical …, 2007 - ascopubs.org
… Results from randomized phase II studies suggest that adding cetuximab to first-line … This
multicenter, noncomparative, open-label, randomized phase II study was designed to evaluate …

[HTML][HTML] Randomized phase II study of first-line carboplatin-paclitaxel with or without bevacizumab in Japanese patients with advanced non-squamous non-small-cell …

S Niho, H Kunitoh, H Nokihara, T Horai, Y Ichinose… - Lung cancer, 2012 - Elsevier
… We report the final results of the randomized phase II study JO19907 in Japan, the only study
in Asia which compared the efficacy and safety of first-line CP with or without bevacizumab …

Combined chemoradiotherapy regimens of paclitaxel and carboplatin for locally advanced non–small-cell lung cancer: a randomized phase II locally advanced multi …

CP Belani, H Choy, P Bonomi, C Scott… - Journal of clinical …, 2005 - ascopubs.org
… This phase II noncomparative randomized trial was conducted to determine the optimal …
TRT), in patients with locally advanced unresected stage III non–small-cell lung cancer (NSCLC). …

… therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre, double-blind randomised phase 3 trial

L Zhang, S Ma, X Song, B Han, Y Cheng… - The lancet …, 2012 - thelancet.com
… on chemotherapy for stage IV non-small-cell lung cancer. … Randomized phase III trial of
platinum-doublet chemotherapy … patients with advanced non-small-cell lung cancer: results of a …

[HTML][HTML] … results for OAK: a randomized phase III study of atezolizumab versus docetaxel in patients with previously treated advanced non–small cell lung cancer

L Fehrenbacher, J von Pawel, K Park… - Journal of thoracic …, 2018 - Elsevier
… against many different tumor types. OAK (NCT02008227) is a randomized phase III study …
However, after the randomized phase II POPLAR study demonstrated survival benefit with …

… of All-Trans-Retinoic Acid With Chemotherapy Based on Paclitaxel and Cisplatin As First-Line Treatment in Patients With Advanced Non–Small-Cell Lung Cancer

O Arrieta, CH González-De la Rosa… - Journal of Clinical …, 2010 - ascopubs.org
Purpose This randomized phase II trial evaluated whether the combination of cisplatin and
paclitaxel (PC) plus all-trans retinoic acid (ATRA) increases response rate (RR) and …

[HTML][HTML] … , randomized phase III trial comparing irinotecan–carboplatin with etoposide–carboplatin as first-line therapy for extensive-disease small-cell lung cancer

A Schmittel, M Sebastian, LF Von Weikersthal… - Annals of oncology, 2011 - Elsevier
… % in the standard arm and an acceptable toxicity in both arms; thus, criteria for extension
into phase III were met [10]. Here, we report the final analysis of the randomized phase III trial. …

Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non–small-cell lung cancer and poor performance …

G Goss, D Ferry, R Wierzbicki, SA Laurie… - Journal of Clinical …, 2009 - ascopubs.org
… patients with advanced non–small-cell lung cancer (NSCLC) and poor performance status.
… This proof of principle randomized phase II study confirms that poor PS patients (PS 2 or 3) …

Randomised phase III trial of irinotecan combined with cisplatin for advanced non-small-cell lung cancer

S Negoro, N Masuda, Y Takada, T Sugiura… - … journal of cancer, 2003 - nature.com
… To determine a standard combination chemotherapy for patients with advanced non-small-cell
lung cancer (NSCLC), we conducted a phase III trial of irinotecan (CPT-11) to test the …

… and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase …

E Quoix, G Zalcman, JP Oster, V Westeel, E Pichon… - The Lancet, 2011 - thelancet.com
… Elderly subgroup analysis of a randomized phase III study of docetaxel plus platinum …
treatment of advanced nonsmall cell lung carcinoma (TAX 326). Cancer. 2005; 104: 2766-2774 …