… -nt RNA duplexes are capable of guiding target RNA cleavage.… RNAs were therefore named
siRNAs (short interfering RNAs) … RNA–protein complexes were referred to as siRNPs (small …

… RNAs (∼20 base pairs) through liposome transfection. We have explored several strategies
for expressing similar short interfering RNA (… using a human U6 small nuclear RNA (snRNA) …

… Small 21- to 25-nucleotide RNAs have diverse biological roles in eukaryotes, including
transposon silencing and antiviral defense by small interfering RNAs (siRNAs) and …

… Increasing knowledge about molecular mechanisms of endogenous RNA interference (RNAi)
and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic acid …

… In the past 2 years, extraordinary developments in RNA interference (RNAi)-based
methodologies have seen small interfering RNAs (siRNA) become the method of choice for …

… We examined the role of ATP in the RNA interference (RNAi) pathway. Our … RNA into
small interfering RNAs (siRNAs), incorporation of siRNAs into an inactive ∼360 kDa protein/RNA …

The discovery of transgene silenc-ing in plants and double-stranded RNA (dsRNA) interference
in the worm Caenorhabditis elegans has led to the latest revolution in molecular biology, …

… [1] and silencing by small RNAs in plants was observed by Hamilton and Baulcombe [2].
The pioneering work on the structure and origin of the small interfering RNAs (siRNAs) came …

… By contrast, the promise of small interfering RNA (siRNA) technology to '… -stranded RNA
(dsRNA); a technology they called RNA interference (RNAi… Introducing the short interfering RNAs …

A major impediment in the treatment of neurological diseases is the presence of the blood–brain
barrier, which precludes the entry of therapeutic molecules from blood to brain. Here we …