… induction of the NQO1 and GST Ya genes. In this study, we demonstrate that overexpression
of small Maf (… expression and tert-butyl hydroquinone induction of the NQO1 and GST Ya …

… In summary, we conclude that the small Maf proteins are essential for the induction of
multiple ARE-dependent genes encoding xenobiotic-metabolizing enzymes and antioxidant …

… ment] type-Maf recognition element (T-MARE; 12). This resemblance provided our initial
insight into the and Nrf2-small Maf heterodimers. role that the small Maf proteins may be an …

… factors Nrf2 and small Maf. Once bound to its recognition DNA sequence termed
antioxidant-responsive element or Maf-recognition element, Nrf2/small Maf induces a set of …

… In conclusion, small Maf protein homodimers and possibly Nrf2/small Maf heterodimers
negatively regulate ARE-mediated expression and antioxidant induction of NQO1 and other …

… The homodimers repress, while small Maf-Nrf2 heterodimers activate… small Maf proteins
stimulates Maf homodimers that repress the ARE-mediated expression and antioxidant induction …

… the ARE as heterodimers with either small Maf proteins, FosB, c-… that affect gene induction
through the ARE is discussed. … blocking agents also induce antioxidant proteins and enzymes …

… recognition element (MARE), NF-E2 as well as the antioxidant response element (ARE)…
induce small Maf gene transcripts significantly. These data suggested that induction of small Maf …

… small Maf proteins lacking the transcriptional activation domain down regulates ARE-mediated
expression and induction. … genes expression and induction in response to anti-oxidants. …

… , as this small MAF protein can induce MATIIA via insulin … Small MAF homodimers and
CNC/small MAF heterodimers recognize MARE sequences, which resemble the antioxidant …