… Inhaled β 2 -adrenoceptor agonists have been the mainstay of bronchodilator therapy for …
and β 2 -adrencoceptor stimulant) isoprenaline, followed by the short-acting β 2 -adrenoceptor-…

… Regular use of LABAs results in β 2 -adrenoceptor down-regulation, receptor internalisation
… by prolonged occupancy of airway β 2 -adrenoceptors. Subsensitivity to methacholine …

… In COPD, unlike in asthma, long-acting β 2 -agonists are recommended as monotherapy
or with a long-acting anticholinergic in all severity classifications of COPD as first choice (except …

… relate to drug actions and clinical outcomes, we discuss their relevance to the recent
controversy regarding the chronic use of β 2 -adrenoceptor agonists in the treatment of asthma. …

… Functional solubilisation of the β2adrenoceptor using diisobutylene maleic acid. Poster
Pharmacology, Edinburgh 2019, Oral presentation European SMALP conference 2020 (…

… evidence that agonism of β 2 -adrenoceptors can lead to the … Therefore, the regulation
by β 2 -adrenoceptor agonists of … In this article, the current status of β 2 -adrenoceptor-mediated …

… They exert their bronchodilatory effects via β 2 adrenoceptors (β 2 ARs) located on airway
smooth muscle (ASM) cells. Activation of these receptors results in ASM, and thus airway, …

… Thus, we have little information as to whether the two β 2 AR pathways can be … β 2 AR, we
screened a 40-million-compound scaffold ranking (SR) library that was agnostic to known β 2 …

Background The benefits of β-blocker therapy may depend on underlying genetic susceptibility.
Methods We investigated the interaction of common variation in β1 and β2 adrenergic …

… This study shows that β 2 -adrenoceptor null mice are resistant to developing airway
hyperresponsiveness, mucous metaplasia, and inflammatory cells in bronchoalveolar lavage fluid, …