… -methylation and pseudouridylation of U2 snRNA take place in the nucleus and are required
for assembly of snRNP-specific proteins. Transport of snRNP particles from the cytoplasm to …

… for nuclear import of the assembled snRNP particles ( … that SMN interacts directly with
several spliceosomal snRNP core Sm proteins, including B/B′ and the D and E group proteins. …

… of SMN is examined within the context of snRNP biogenesis and evidence is examined which
suggests that the SMN functional defects in snRNP … and maturation of snRNP particles and …

… which is closely related to the ubiquitously expressed SmB protein but is expressed …
SmN, its localisation within different snRNP particles was Investigated using a range of antl-snRNP …

… ample evidence that SMN, in the context of the multiprotein SMN complex, … snRNPs and
possibly other RNP particles. Detailed molecular studies of snRNP assembly revealed that SMN …

… particles (snRNPs) requires the activity of the survival of motor neurons (SMN) protein complex
(… Thus we conclude that SMN remains bound to Sm snRNPs after cap hypermethylation, …

… They were discovered more than 40 years ago by Lerner and Steitz as RNA components
of small nuclear ribonucleoprotein particles (snRNPs) co-precipitating with Sm proteins 1 . …

… the SMN–SIP1 complex interacts with U1 and U5 snRNAs in the cytoplasm but not after these
snRNAs have been assembled into snRNPs … and/or in the nuclear import of these particles. …

… of small nuclear ribonucleoprotein particles (snRNPs). Complete depletion of the SMN
complex from cell extracts abolishes snRNP assembly, the formation of heptameric Sm cores on …

… Moreover, we showed that Gemin5, which is the snRNA binding protein of the SMN
complex, interacts in vitro with the 7S RNA. These observations motivated us to investigate a …