DNA adducts in different tissues of smokers and nonsmokers

J Cuzick, MN Routledge, D Jenkins… - International journal of …, 1990 - Wiley Online Library
… cigarette smoking to DNA adducts in the lung and shown that similar patterns of adducts are
found in the bladder and pancreas, but at lower levels. There are large variations in adduct

DNA adducts as markers of exposure and risk

DH Phillips - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
… of smoking-related DNA adducts in the tissues of smokers, ex-smokers and non-smokers [16]. …
level of DNA adducts in smokers, compared with non-smokers, confirming the validity of …

Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers

PG Foiles, SA Akerkar, SG Carmella… - Chemical research in …, 1991 - ACS Publications
… of HPB-releasing adducts in peripheral lung DNA of smokers to be 0.5 adducts/10®
nucleotides. In our previous study of tobacco-specific nitrosamine hemoglobin adducts in users of …

DNA adducts in lymphocytes and granulocytes of smokers and nonsmokers detected by the 32P-postlalbelling assay

K Savela, K Hemminki - Carcinogenesis, 1991 - academic.oup.com
… cytes of 11 smokers and 10 nonsmokers to determine any smoking-related DNA adducts by
the … the mean lymphocyte DNA adducts/108 nucleotides of 31 ± 5.7 (SE) of smokers were …

DNA adducts in cervical tissue of smokers and non-smokers

DH Phillips, MN Shé - Mutation Research/Environmental Mutagenesis and …, 1994 - Elsevier
… In a pilot study (Phillips et al., 1990a), the presence of DNA adducts was detected in … smokers
and non-smokers were significant. More recently, we have demonstrated that DNA adduct

DNA adducts in human tissues: biomarkers of exposure to carcinogens in tobacco smoke.

DH Phillips - Environmental health perspectives, 1996 - ehp.niehs.nih.gov
… such as the level of DNA adducts. Of more immediate interest is … the DNA adducts formed
in the tissuesof smokers. In recent … DNA adducts in lymphocytes of smokers and nonsmokers

Recent studies on DNA adducts resulting from human exposure to tobacco smoke

B Ma, I Stepanov, SS Hecht - Toxics, 2019 - mdpi.com
… since 2012 on DNA adduct formation in smokers. A variety of DNA adducts derived from …
We analyzed the levels of Acr-dG adducts in lung DNA of 19 smokers and 18 nonsmokers

DNA adducfs, protein adducts, and sister chromatid exchange in cigarette smokers and nonsmokers

FP Perera, RM Santella, D Brenner… - Journal of the …, 1987 - academic.oup.com
… (sample 3) but not for nonsmokers. In sample 1, this correlation was positive though …
negative in nonsmokers. Since 4-ABP is a more direct marker of smoking than PAH-DNA adducts, …

Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking

R Godschalk, J Nair, FJ Van Schooten, A Risch… - …, 2002 - academic.oup.com
… In the present study, we also have detected O 4 etT and PAH–DNA adducts in lung DNA
of non-smokers. The source of these background levels could be the environment, …

DNA and protein adducts in human tissues resulting from exposure to tobacco smoke

DH Phillips, S Venitt - International journal of cancer, 2012 - Wiley Online Library
smokers and nonsmokers by both methods. Associations between normal lung and blood
DNA adducts correlated only for nonsmokers, … current smokers, and 4-ABP-DNA adducts were …