… of a novel BRAF mutation in a case of a solid variant of PTC. This mutation was detected in
1 … of BRAF mutations, there appears to exist, in PTC, a close association between the type of …

… BRAF gene mutations are identified in about 45% of … of PTC, solid variant, with a complex
BRAF mutation that involves one … This mutation leads to the replacement of a threonine with an …

… states that the term “solid variant” should only be used when … to any of the other PTC variants
has a solid, trabecular, or … BRAF mutation can be found in the majority of tall cell variant …

… Because vemurafenib is a targeted therapy, methods that detect mutant BRAF in melanoma
… to identify DNA variants in many contexts, including BRAF mutation testing in solid tumors. It …

… of BRAF V600E and RAS mutations … BRAF V600E mutation status documented by molecular
or immunohistochemistry essays. Subsequently, the status RAS or BRAF V600E mutations …

… these, 1 had a BRAF fusion and 31 had BRAF mutations (13 and 19 with class 2 and 3
mutations, … II study of trametinib in patients with BRAF fusions, or with non-V600 BRAF mutations. …

… we explored the spectrum and frequencies of BRAF mutations in a large cohort of solid
tumors and analyzed other potentially targetable biomarkers co-existing with BRAF mutations. …

… cytology with the detection of the BRAF VK600-1E mutation, the molecular hallmark of the
… conclude that the BRAF triplet detection is of value as a predictive marker of solid variant on …

… BRAF mutations to present-day clinical intervention strategies. We delve into the role of the
BRAF … , as combinatorial approaches to treat cancer types harboring BRAF hotspot mutations. …

… [ERC1:BRAF in a melanoma sample negative for BRAF mutation (MO-17) and TPR:NTRK1
in a colon cancer (MO-35)], validating both fusions by qPCR. Of note, ERC1:BRAF was not …