Cosolvent effect on solubility of aripiprazole in mixed solvents and apparent thermodynamic analysis of dissolution process
Y Wu, L Cheng, J Wu, M Zhai, L Cai - The Journal of Chemical …, 2019 - Elsevier
… as solubility, stability and dissolution rate. In this work, we study the shape of the solubility
… The solubility value is a function of temperature and solvent composition. It increases at first …
… The solubility value is a function of temperature and solvent composition. It increases at first …
Improving the solubility of aripiprazole by multicomponent crystallization
Q Zhou, Z Tan, D Yang, J Tu, Y Wang, Y Zhang, Y Liu… - Crystals, 2021 - mdpi.com
… in vivo dissolution and reflect bioavailability of drugs [31]. In this work, IDR was measured
by the rotary basket method, which was applied to distinguish their dissolution properties. Prior …
by the rotary basket method, which was applied to distinguish their dissolution properties. Prior …
Improvement of aripiprazole solubility by complexation with (2-hydroxy) propyl-β-cyclodextrin using spray drying technique
T Mihajlovic, K Kachrimanis, A Graovac, Z Djuric… - Aaps Pharmscitech, 2012 - Springer
… grid map generation and result clustering procedures (7). The starting coordinates of … and
ionic composition of the dissolution medium on the solubility of aripiprazole in the presence of …
ionic composition of the dissolution medium on the solubility of aripiprazole in the presence of …
Comparison of nanomilling and coprecipitation on the enhancement of in vitro dissolution rate of poorly water-soluble model drug aripiprazole
AA Abdelbary, X Li, M El-Nabarawi… - Pharmaceutical …, 2014 - Taylor & Francis
… An isocratic HPLC method was employed for the quantification of aripiprazoleCitation23.
A Thermo Separation HPLC system (Fremont, CA) equipped with a P4000 pump unit, an …
A Thermo Separation HPLC system (Fremont, CA) equipped with a P4000 pump unit, an …
The Effect of Intermolecular Interactions on the Dissolution Property of Aripiprazole
… In this work, the solubilities of aripiprazole (APZ) in 11 pure … After the solubility is obtained,
the solubility data can usually … the dissolution process (eg, dissolution enthalpy, dissolution …
the solubility data can usually … the dissolution process (eg, dissolution enthalpy, dissolution …
In vitro dissolution–permeation evaluation of an electrospun cyclodextrin-based formulation of aripiprazole using μFlux™
… soluble candidates is continually increasing, dissolution enhancement of poorly water soluble
… , while this low polymer concentration still enabled fiber formation by the ES process. The …
… , while this low polymer concentration still enabled fiber formation by the ES process. The …
Enhanced dissolution, permeation and oral bioavailability of aripiprazole mixed micelles: In vitro and in vivo evaluation
… Aripiprazole (ARP) is an antipsychotic drug approved for the treatment of schizophrenia. It
is poorly water-soluble … solution and Abilify® were carried out with the dialysis bag method (…
is poorly water-soluble … solution and Abilify® were carried out with the dialysis bag method (…
New cocrystals of antipsychotic drug aripiprazole: Decreasing the dissolution through cocrystallization
W Liu, R Ma, F Liang, C Duan, G Zhang, Y Chen… - Molecules, 2021 - mdpi.com
… in order to adjust the solubility and dissolution rate, we choose … method, anti-solvent method,
and liquid-assisted grinding … method on FADT-1202RC automatic sampling dissolution …
and liquid-assisted grinding … method on FADT-1202RC automatic sampling dissolution …
[PDF][PDF] Solubility enhancement of aripiprazole by solid-self emulsifying drug delivery systems
A Chennuri, D Prasanthi - International Journal of Pharmaceutical …, 2018 - researchgate.net
… method to prepare the solid SMEDDS tablets from liquid SMEDDS, which can enhance the
solubility and improve the in-vitro drug release of aripiprazole. … the solubility and dissolution …
solubility and improve the in-vitro drug release of aripiprazole. … the solubility and dissolution …
Establishment of In Vitro Dissolution Based on Similarity with In Vivo Dissolution: A Case Study on Aripiprazole
… measuring the in vivo dissolution, because the dissolution process is accompanied by a
gradual … APZ belongs to BCS class II due to the equilibrium solubility of 0.00001% (w/v) and the …
gradual … APZ belongs to BCS class II due to the equilibrium solubility of 0.00001% (w/v) and the …