… sepsis once again underlining the central role of apoptosis in sepsis pathogenesis. Recent
studies indicate upregulation of the pro-apoptotic genes BID and FAS in septic shock patients…

… Fas/Fas ligand (FasL) signaling has emerged as an important … Septic shock was defined as
sepsis with acute persistent … routine adjuvant treatment for septic shock. Seventeen healthy …

… as INR, aPTT, platelets, septic shock, lactic acid, creatinine and adequate empiric antimicrobial
treatment. Besides, that serum soluble Fas concentrations could be used for mortality …

… septic shock and our results showing significantly higher levels of sFas in septic shock patients
compared to normotensive septic … during polymicrobial sepsis is a Fas ligand but not an …

… syndrome), sepsis, severe sepsis, or septic shock. Inflammatory … [MMPs]) and soluble
FAS‐Ligand (sCD178) were … SIRS, 5 suffered from sepsis (2 died), and 13 had septic shock (5 …

Objective: We asked whether the analysis of pro-or antiapoptosis contribute to our understanding
of immune dysfunction, hyperinflammation and/or resolution of sepsis and septic shock…

… liver cells via the FasL/Fas system is considered the most important mechanism in this
process. Thus we measured TNF-α, soluble FasL (sFasL), and soluble Fas (sFas) in patients with …

… Additionally, it has been suggested that soluble FasL in circulation may also play some role
in a paracrine regulation of apoptosis [35]. However, soluble FasL concentration in plasma …

… Citation 44 , Citation 45 These reports suggested the involvement of FADD in organ injury
during septic shock. In this study, FADD protein expressions were unaltered in renal cortical …

… We found that CD14 expression is down-regulated in monocytes from septic shock … soluble
Fas ligand and membrane-bound Fas ligand cytotoxic activity. Unconjugated anti-Fas Abs (…