Solvent influence on manufacturability, phase behavior and morphology of amorphous solid dispersions prepared via bead coating

E Boel, F Giacomini, G Van den Mooter - European Journal of …, 2021 - Elsevier
… However, the impact of solvent selection on the bead coating … the influence of the solvent
on the bead coating process itself … of the resulting ASDs coated onto beads. For this purpose, …

Influence of processing and curing conditions on beads coated with an aqueous dispersion of cellulose acetate phthalate

RO Williams III, J Liu - European Journal of Pharmaceutics and …, 2000 - Elsevier
… In this study, the influence of processing variables on film formation from beads coated with
Aquacoat ® CPD was investigated. Three important processing variables, including outlet …

Development of a surface coating technique with predictive value for bead coating in the manufacturing of amorphous solid dispersions

E Boel, P Panini, G Van den Mooter - Pharmaceutics, 2020 - mdpi.com
… with spray drying or bead coating, given the low rate of solvent evaporation. This research
… However, since the employed solvent system can have an influence on the classification …

Bead coating process via an excess of crosslinking agent

V Iannuccelli, G Coppi, MA Vandelli, E Leo… - Drug development …, 1995 - Taylor & Francis
… The dynamic swelling analysis allowed to exclude the influencesolvent during the drying
process can also affect the c:oncentration distribution of the drug. In fact, only when the solvent

Solventless pharmaceutical coating processes: a review

S Bose, RH Bogner - Pharmaceutical development and technology, 2007 - Taylor & Francis
solvent in the coatings and high cost of organic solvents and … They demonstrated that the
coating of glass beads with … and pressure, PVCVA was coated onto the beads without the use of …

Design space for a solventless photocurable pharmaceutical coating

S Bose, B Kelly, RH Bogner - Journal of Pharmaceutical Innovation, 2006 - Springer
… toxicity of the residual solvent in the coatings, and the high cost of organic solvents and their
… pareil beads in a mini-coating pan. The beads were exposed to light after each coating layer…

[HTML][HTML] The Value of Bead Coating in the Manufacturing of Amorphous Solid Dispersions: A Comparative Evaluation with Spray Drying

E Boel, F Reniers, W Dehaen, G Van den Mooter - Pharmaceutics, 2022 - mdpi.com
… , even though spray drying (ie, T inlet ) operated at the boiling point of the solvent and the
T bed during the bead coating procedure was about 40 C. Moreover, the rate of solid phase …

Solventless visible light-curable coating: I. Critical formulation and processing parameters

S Bose, RH Bogner - International journal of pharmaceutics, 2010 - Elsevier
… with the use of solvents including water, several solventless coating techniques are being …
the weight of single coated beads to the total weight of coated beads obtained in the process (…

The limits of edge bead planarization and surface levelling in spin-coated liquid films

S Arscott - Journal of Micromechanics and Microengineering, 2020 - iopscience.iop.org
… , solvents trapped in the drying thick edge beads can cause film cracking and debris ejection
onto the wafer surface. Edge beads … are used to illustrate the influence of this parameter on …

Stabilization of solvent-impregnated resin capacities by different techniques

D Muraviev, L Ghantous, M Valiente - Reactive and Functional Polymers, 1998 - Elsevier
… A detailed analysis of the factors influencing the stability of SIR capacity … beads that results
to the high stability of the bead coating. At the same time, note that insufficient time of beads