Prospective genomic profiling of prostate cancer across disease states reveals germline and somatic alterations that may affect clinical decision making
… Likewise, we found that somatic alterations in BRCA2 were present … somatic BRCA2 loss
of function alterations occur early in tumorigenesis for affected patients. Conversely, alterations …
of function alterations occur early in tumorigenesis for affected patients. Conversely, alterations …
Somatic genomic changes in single Alzheimer's disease neurons
… individuals with Alzheimer’s disease and neurotypical control individuals. We found that
somatic DNA alterations increase in individuals with Alzheimer’s disease, with distinct molecular …
somatic DNA alterations increase in individuals with Alzheimer’s disease, with distinct molecular …
Somatic genome variations in health and disease
… alterations in somatic cells. Experimental data do demonstrate such genomic variations to
exist and to be involved in human development and interindividual genetic variability in health …
exist and to be involved in human development and interindividual genetic variability in health …
[HTML][HTML] The altered somatic brain network in state anxiety
X Li, M Zhang, K Li, F Zou, Y Wang, X Wu… - Frontiers in …, 2019 - frontiersin.org
… Based on the functions of the postcentral gyrus and the somatic marker … of state anxiety
and that this abnormal neural activity would be correlated with the mechanism underlying state …
and that this abnormal neural activity would be correlated with the mechanism underlying state …
Diverse somatic mutation patterns and pathway alterations in human cancers
Z Kan, BS Jaiswal, J Stinson, V Janakiraman, D Bhatt… - Nature, 2010 - nature.com
… of somatic mutations in cancer genomes is essential for understanding the disease and
for developing targeted therapeutics 1 . Here we report the identification of 2,576 somatic …
for developing targeted therapeutics 1 . Here we report the identification of 2,576 somatic …
Brain functional alterations in MDD patients with somatic symptoms: a resting-state fMRI study
P Liu, H Tu, A Zhang, C Yang, Z Liu, L Lei, P Wu… - Journal of Affective …, 2021 - Elsevier
… with somatic symptoms based on ReHo and ALFF values. Further more, in addition to exploring
the relationship between brain function and somatic … symptoms and somatic symptoms. …
the relationship between brain function and somatic … symptoms and somatic symptoms. …
[PDF][PDF] Somatic alterations in the human cancer genome
B Weir, X Zhao, M Meyerson - Cancer cell, 2004 - cell.com
… Most human malignancies are caused by somatic alterations … to identify cancer genome
alterations, including point mutations, … led to the discovery of somatic mutations in the BRAF, …
alterations, including point mutations, … led to the discovery of somatic mutations in the BRAF, …
The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology
X Matias-Guiu, G Stanta, F Carneiro, A Ryska… - Virchows Archiv, 2020 - Springer
… somatic alterations of cancer. In this article, we emphasize the importance of interpreting
somatic molecular alterations of … and interpretation of somatic molecular alterations in cancer. …
somatic molecular alterations of … and interpretation of somatic molecular alterations in cancer. …
[HTML][HTML] Somatic symptoms disorders in Parkinson's disease are related to default mode and salience network dysfunction
… Our results confirm that functional alterations in the brains of SSD patients are bilateral (Atmaca
et al., 2011; Garcia-Campayo et al., 2001; Hakala et al., 2004; Lemche et al., 2013; Su et …
et al., 2011; Garcia-Campayo et al., 2001; Hakala et al., 2004; Lemche et al., 2013; Su et …
Somatic mutations in rheumatological diseases: VEXAS syndrome and beyond
KA Sikora, KV Wells, EC Bolek, AI Jones… - …, 2022 - academic.oup.com
… In contrast to germline mutations, alterations in … somatic hypermutation in proliferating
germinal centre B cells [5]. Genetic analysis of tissues in healthy individuals and in disease states …
germinal centre B cells [5]. Genetic analysis of tissues in healthy individuals and in disease states …
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