… cell lines which express endogenous somatostatin receptors [50]. The fact that these tumour
cells express multiple somatostatin receptors … of whether different somatostatin receptor(s) …

… and tumour cell proliferation. It exerts its effects through interaction with five somatostatin
receptors (sst1–sst5), which belong to the family of G-protein-coupled receptors with seven …

… inhibition of cell proliferation, we investigated cellular effector … involved in the antimitogenic
effect of somatostatin (1, 2, 10, … of cell proliferation by RC-160 in SSTR2expressing cells was …

… tyrosine phosphatase is coeluted with somatostatin receptor, suggesting that tyrosine …
promoted by somatostatin receptor occupancy (16). The somatostatin receptor subtypes and the …

… of somatostatin are mediated through five high affinity plasma membrane receptors [somatostatin
receptor … , and stimulate endothelial and smooth muscle cell proliferation and migration, …

… were significantly more potent in inhibiting LNCaP cell proliferation than BIM-23120 (sst 2 )
… reduced cell proliferation, whereas exposure to BIM-23704 resulted in a lower cell growth …

… cell proliferation was significantly inhibited by SST-14, lanreotide, BIM-23190, and BIM-23268
in 4, 7, 3, and 4 tumors, respectively (range of proliferation … on tumor cell proliferation and …

… (PTPs) by somatostatin receptor (SSTR) represents one of the … in the antiproliferative
effect of somatostatin (SST) and … cell functions including cell proliferation, differentiation, cell …

… cell proliferation, survival and angiogenesis. This provided the rationale for developing
multireceptor-targeted somatostatin … the development of rabiolabeled somatostatin analogs have …

… somatostatin receptor biology and signaling. SOMATOSTATIN AND SOMATOSTATIN RECEPTOR
… Inhibition of mitogen-induced cell proliferation triggered by the NO signaling system is …