Alopecuroides A–E, Matrine-Type Alkaloid Dimers from the Aerial Parts of Sophora alopecuroides

CL Fan, YB Zhang, Y Chen, P Xie… - Journal of natural …, 2019 - ACS Publications
… In summary, five alkaloid dimers were isolated from the aerial parts of S. alopecuroides.
Of note, compound 2 showed a stronger anti-inflammatory effect than matrine, indicating its …

Three quinolizidine dimers from the seeds of Sophora alopecuroides and their hepatoprotective activities

X Yuan, J Jiang, Y Yang, X Zhang, Z Feng… - Chinese Chemical …, 2022 - Elsevier
… study, three new alkaloid dimers were isolated and identified from S. alopecuroides, namely
… first [2 + 2] cycloaddition dimeric matrine-based alkaloid possessing an unprecedented 6/6/6…

Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L

C Meng, Y Wang, S Chen, M Li, C Yuan… - Bioorganic & Medicinal …, 2022 - Elsevier
… (A) Structures of known dimeric alkaloids from Sophora alopecuroides L.(ag); (B) Chemical
… novel skeleton dimer alkaloids CMs were first isolated from Sophora alopecuroides. They …

Structurally Diverse Matrine‐Based Alkaloids with Anti‐inflammatory Effects from Sophora alopecuroides

D Luo, NH Chen, WZ Wang, JH Zhang… - Chinese Journal of …, 2021 - Wiley Online Library
… to flavesine D (2), [22] a dimeric alkaloid assembled by sophocarpine and matrine via a C-13—C-…
Herein, compound 1 was defined as a novel dimeric matrine-type skeleton assembled …

Aloperine-Type Alkaloids with Antiviral and Antifungal Activities from the Seeds of Sophora alopecuroides L.

ZX Hu, J Zhang, T Zhang, CY Tian, Q An… - Journal of Agricultural …, 2024 - ACS Publications
… pesticides from natural quinolizidine alkaloids, the chemical compositions of the seeds of
Sophora alopecuroides were thoroughly researched. Fifteen new aloperine-type alkaloids (1–…

Alopecines A–E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides

XF Wang, Z Zhu, TT Hao, QQ Fang, K Jiang, SJ Qu… - Bioorganic …, 2020 - Elsevier
… In summary, the phytochemical investigation of the seeds of Sophora alopecuroides led to
the isolation of five unusual Cl-containing matrine-type alkaloids, alopecines A–E (1–5). The …

Water-soluble matrine-type alkaloids with potential anti-neuroinflammatory activities from the seeds of Sophora alopecuroides

D Luo, Q Lin, JL Tan, HY Zhao, X Feng, NH Chen… - Bioorganic …, 2021 - Elsevier
alkaloids from water-soluble part of Sophora alopecuroides led to obtain forty matrine-type
alkaloids … Notably, eight compounds (1–8) belong to rare bis-amide matrine-type alkaloid. The …

Undescribed matrine-type alkaloids from Sophora alopecuroides with anti-inflammatory activity

D Luo, JW Zou, JH Wang, H Tian, HY Xie, TX Zhu… - Phytochemistry, 2024 - Elsevier
alkaloid fractions of Sophora alopecuroides L. led to the production of 11 undescribed
matrine-type alkaloids, … The key structure-activity relationships of those matrine-type alkaloids for …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
… Forty-three quinolizidine alkaloids (1–43), including … Sophora alopecuroides. Structurally,
compounds 1–4 were the first examples of C-11 oxidized matrine-type alkaloids from Sophora

Four Matrine-Based Alkaloids with Antiviral Activities against HBV from the Seeds of Sophora alopecuroides

YB Zhang, XL Zhang, NH Chen, ZN Wu, WC Ye… - Organic …, 2017 - ACS Publications
… We recently reported several novel dimeric matrine-type alkaloids from the Sophora plant (…
of effective constituents in total alkaloids from Sophora alopecuroides L. and their joint action …